Acta Med. 2008, 51: 3-12

Antimicrobial Agents Used in Endodontic Treatment

Marina George Kudiyirickal, Romana Ivančaková

Charles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, Department of Dentistry, Hradec Králové, Czech Republic

Received November 1, 2007
Accepted February 1, 2008

Biomechanical preparation alone does not completely eradicate microorganisms from the root canal, hence the next logical step is to perform root canal procedures in conjunction with antimicrobials. The use of an antimicrobial agent improves the efficacy and prognosis of endodontic treatment. This review enumerates the most widely used antimicrobial agents, their mechanism of action and their potential use in reducing the microbial load.


This paper has been supported by the Grant Agency of Ministry of Education, Youth and Physical Training, no. 2B06104.


139 live references