A Delayed Fatal Metastatic Hürthle Cell Carcinoma

Noordally, S. Oaleed; Sohawon, Schoeb; Duttmann, Ruth; Spinato, Linda; Kleynen, Pierre; Verougstraete, Georges

doi:10.14712/18059694.2016.26

Acta Medica > Archive > 2011, Vol. 54 > Issue 2 > A Delayed Fatal Metastatic Hürthle Cell…

Acta Med. 2011, 54: 87-89

https://doi.org/10.14712/18059694.2016.26

A Delayed Fatal Metastatic Hürthle Cell Carcinoma

S. Oaleed Noordally^a, Schoeb Sohawon^b, Ruth Duttmann^c, Linda Spinato^d, Pierre Kleynen^e, Georges Verougstraete^d

^aCHU Brugmann, Free University of Brussels, Department of Critical Care Medicine, Brussels, Belgium
^bCHU Brugmann, Free University of Brussels, Department of Surgery, Erasme Hospital, Brussels, Belgium
^cCHU Brugmann, Free University of Brussels, Department of Pathology, Brussels, Belgium
^dCHU Brugmann, Free University of Brussels, Department of Otolaryngology and Cervico-Facial Surgery, Brussels, Belgium
^eCHU Brugmann, Free University of Brussels, Department of Endocrinology, Brussels, Belgium

Received September 11, 2010
Accepted February 11, 2011

Hürthle (oxyphilic or oncocytic) cell carcinoma is a variant of follicular cell carcinoma of thyroid. Although this entity of thyroid cancer is well known, its occurrence in young patients has scarcely been reported. We report a case of a 26 year-old male patient, at the time of diagnosis, of Turkish origin, who developed a tracheal, pulmonary and mediastinal metastatic Hürthle cell carcinoma with bilateral cervical and mediastinal lymphadenopathies. This case illustrates an aggressive and metastatic cancer at the time of diagnosis and resistant to all treatment options including surgery, chemotherapy and radioactive iodine.