Nasal Polyposis and Fungal <i>Schizophyllum Commune</i> Infection: A Case Report

Perić, Aleksandar; Vojvodić, Danilo; Zolotarevski, Lidija; Perić, Aneta

doi:10.14712/18059694.2016.25

Acta Medica > Archive > 2011, Vol. 54 > Issue 2 > Nasal Polyposis and Fungal…

Acta Med. 2011, 54: 83-86

https://doi.org/10.14712/18059694.2016.25

Nasal Polyposis and Fungal Schizophyllum Commune Infection: A Case Report

Aleksandar Perić^a, Danilo Vojvodić^b, Lidija Zolotarevski^c, Aneta Perić^d

^aClinic of Otorhinolaryngology, Department of Rhinology, Military Medical Academy, Belgrade, Serbia
^bInstitute of Medical Research, Department of Clinical Immunology, Military Medical Academy, Belgrade, Serbia
^cInstitute of Pathology, Military Medical Academy, Belgrade, Serbia
^dInstitute of Pharmacy, Military Medical Academy, Belgrade, Serbia

Received November 24, 2010
Accepted December 29, 2010

We present a rare case of eosinophilic fungal rhinosinusitis with nasal polyps in a 32-year-old woman caused by basidiomycete fungus Schizophyllum commune. Diagnosis was done by the endoscopic nasal examination, computed tomography (CT) of the paranasal sinuses, the histopathological examination of polyps, the presence of eosinophils and fungal hyphae in nasal mucus and by the detection of S. commune by culture. The patient was successfully treated by combination of oral itraconazole and topical corticosteroid therapy combined with surgery. The pathogenesis and diagnosis of allergic fungal rhinosinusitis are also discussed.