Acta Med. 2026, 69: 72-74

https://doi.org/10.14712/18059694.2026.21

The Changing Comorbidity Burden and its Association with Outcomes in Acute NIV: A Charlson Comorbidity Index-Based Analysis

Aylin Ozsancak Ugurlua, Alastair Watsonb,c, Barea Tanveera, Syed Abida, Giselle Pereiraa, Rahul Mukherjeea

aDepartment of Respiratory Medicine, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, United Kingdom
bCambridge University Hospitals NHS Foundation Trust, United Kingdom
cSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

Received May 8, 2026
Accepted June 9, 2026

References

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2. Masip J, Roque M, Sánchez B, et al. Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis. JAMA. 2005 Dec; 294(24): 3124–30. <https://doi.org/10.1001/jama.294.24.3124>
3. Ozsancak Ugurlu A, Watson A, Ellis P, et al. Predicting in-hospital mortality in a real-world population of ward-based non-invasive ventilation in acute COPD exacerbations. Ther Adv Respir Dis. 2026; 20: 17534666261441160. <https://doi.org/10.1177/17534666261441160> <PubMed>
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7. Ozsancak Ugurlu A, Watson A, Ellis P, et al. P234 Predicting in-hospital mortality in a real-world population of ward-based non-invasive ventilation (NIV) in acute exacerbations of COPD. Thorax. 2025; 80: A292–3.
8. Watson A, Barnard H, Antoine-Pitterson P, et al. The impact of COVID-19 on acute non-invasive ventilation services: A case for change. Respirology. 2021; 26: 1106–9. <https://doi.org/10.1111/resp.14156> <PubMed>
9. AlHelou A, Watson A, Russell K, et al. Technology-enabled multidisciplinary team in-reach for oral corticosteroid stewardship and optimizing care of suspected airways disease exacerbations. Acute Med. 2022; 21(4): 205–6. <https://doi.org/10.52964/AMJA.0926>
10. Balu A, Watson A, Linhartova L, et al. P14 The role of a Ventilation Multidisciplinary team meeting (VMDT) in optimising critical care resource-use. Thorax. 2021; 76: A74.
11. Watson A, Barnard H, Shanmugarajah A, et al. Response times for acute non-invasive ventilation set-ups. Ulster Med J. 2022 Sep; 91(3): 169–70.
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13. Balu A, Watson A, Linhartova L, Ellis P, Mukherjee R. COVID-19 highlights the need to optimize critical care resource use: The role of a respiratory-led multidisciplinary team. Respirology. 2021 Aug; 26(8): 727–8. <https://doi.org/10.1111/resp.14090> <PubMed>
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