Acta Med. 2025, 68: 167-169

https://doi.org/10.14712/18059694.2026.8

“A Paralyzing Snack”: An Endocrine Cause of Paralysis

Ferdinando RombolaaID, Marianna RodolicobID

aInternal Medicine, Vibo Valentia Hospital, Italy
bEmergency Medicine, Vibo Valentia Hospital, Italy

Received September 17, 2025
Accepted December 2, 2025

A case of a young Caucasian man presenting to the Emergency Department (ED) with lower limb weakness, anxiety, and sweating is described. Clinical and laboratory evaluations revealed severe hypokalemia (1.4 mmol/L) associated with thyrotoxicosis, leading to a diagnosis of Thyrotoxic Periodic Paralysis (TPP). After initial improvement following potassium infusion, the patient experienced symptom exacerbation. Further investigation linked the recurrence to excessive carbohydrate intake from vending machine snacks. TPP, a complication of hyperthyroidism, is extremely rare in Western countries but must be promptly recognized due to its potential life-threatening complications.

References

22 live references