Acta Med. 2022, 65: 144-148

https://doi.org/10.14712/18059694.2023.5

Association of Giant Cell Arteritis with Papillary Thyroid Carcinoma

Lucia Šípováa, Barbora Havlínováb, Martina Bělobrádkováa, Leoš Ungermannc, Tomáš Soukupa

aDivision of Rheumatology, 2nd Department of Internal Medicine – Gastroenterology, University Hospital Hradec Králové, Faculty of Medicine Hradec Králové, Charles University, Hradec Králové Czech Republic
b4th Department of Internal Medicine – Hematology, University Hospital Hradec Králové, Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic
cDepartment of Radiology, Faculty of Health-Care Study, Pardubice University, District Hospital Pardubice, Czech Republic

Received June 13, 2022
Accepted January 11, 2023

Previous studies suggest that there may be an association between cancer and autoimmune diseases. We describe the case of a 59-year-old patient who did not have any significant diseases in the last year. She had new onset of fever of unknown aetiology, headache, fatigue and night sweats. We used laboratory methods to rule out infectious diseases. Significant laboratory findings reported increased signs of inflammation and anti-nuclear antibody (ANA) positivity. Positron emission tomography/computed tomography (PET/CT) imaging showed the origin of the patient’s difficulties, arteritis, with increased metabolic activity in the aortic wall and other arteries. Doppler ultrasonography of the arteries did not show pathology in the temporal arteries but found accelerated blood flow in the superior mesenteric artery (AMS). Another finding from PET/CT was a tumour in the thyroid gland, later verified histologically as papillary thyroid carcinoma (PTC). We investigated the link between rheumatological disease and papillary carcinoma, applying similar therapy, corticosteroids and immunosuppressants.

References

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