Acta Med. 2021, 64: 193-199
https://doi.org/10.14712/18059694.2022.1
Endoscopic Injection Treatment of Vesicoureteral Reflux in Children: Meeting with the Factors Involved in the Success Rate
References
1. Clin Pediatr 2014; 53: 1119–33.
< S, Sinopidis X, Karatza A, Varvarigou A. Predictive risk factors in childhood urinary tract infection, vesicoureteral reflux, and renal scarring management. https://doi.org/10.1177/0009922813515744>
2. Minerva Urol Nefrol 2017; 69: 144–52.
S, Sinopidis X, Tsikopoulos G, Spyridakis I, Karatza A, Varvarigou A. Dimercaptosuccinic acid scan challenges in childhood urinary tract infection, vesicoureteral reflux and renal scarring investigation and management.
3. Eur Urol Foc 2017; 3: 181–8.
< P, Burgu B. Contemporary Management of Vesicoureteral Reflux. https://doi.org/10.1016/j.euf.2017.08.012>
4. Investig Clin Urol 2017; 58: 38–45.
< SW, Lee YS, Han SW. Endoscopic injection therapy. https://doi.org/10.4111/icu.2017.58.S1.S38>
<PubMed>
5. Der Urologe Ausg A 1981; 20: 263–4.
E. Treatment of vesicorenal reflux by transurethral teflon- injection.
6. Br Med J (Clin Res Ed) 1984; 289: 7–9.
< b, Puri P. Treatment of vesicoureteric reflux by endoscopic injection of Teflon. https://doi.org/10.1136/bmj.289.6436.7>
<PubMed>
7. J Urol 1995; 154: 800–3.
< A, Lackgrten G. A new bioimplant for the endoscopic treatment of vesicoureteral reflux: Experimental and short-term clinical result. https://doi.org/10.1016/S0022-5347(01)67168-4>
8. Urology 2017; 110: 196–200.
< S, Gómez-Fraile A, Carrillo-Arroyo I, Tordable-Ojeda C, Cabezalí-Barbancho D. Endoscopic Treatment of Vesicoureteral Reflux in Infants. Can We Do It and Should We Do It? https://doi.org/10.1016/j.urology.2017.08.005>
9. BJU Int 2010; 105: 1332–47.
< G, Kirsch AJ. Surgery Illustrated – Surgical Atlas Endoscopic treatment of vesicoureteral reflux. https://doi.org/10.1111/j.1464-410X.2010.09325.x>
10. BJU Int 2003; 92: 285–8.
< N, Lais A, Matarazzo E, Nappo S, Patricolo M, Caione P. Treatment of vesico-ureteric reflux: A new algorithm based parental preference. https://doi.org/10.1046/j.1464-410X.2003.04325.x>
11. Front Pediatr 2019; 7: 392.
< M, Bilgutay AN, Tollin N, et al. Long-Term clinical outcomes and parental satisfaction after Dextranomer/Hyaluronic acid (Dx/ HA) injection for primary vesicoureteral reflux. https://doi.org/10.3389/fped.2019.00392>
<PubMed>
12. Korean J Pediatr 2013; 56: 145–50.
< JW, Oh MM. Endoscopic treatment of vesicoureteral reflux in pediatric patients. https://doi.org/10.3345/kjp.2013.56.4.145>
<PubMed>
13. J Pediatr Urol 2013; 9: 483–7.
< L, Rovira J, Blazquez-Gomez E, et al. Randomized clinical trial comparing endoscopic treatment with dextranomer hyaluronic acid copolymer and Cohen’s ureteral reimplantation for vesicoureteral reflux: long-term results. https://doi.org/10.1016/j.jpurol.2013.03.003>
14. J Urol 2009; 182: 1703–7.
< B, Natsheh A, Fridmans A, Shenfeld OZ, Farkas A. Renal scarring and urinary tract infection after successful endoscopic correction of vesicoureteral reflux. https://doi.org/10.1016/j.juro.2009.03.011>
15. Cent European J Urol 2015; 68: 389–95.
< B, Berger C, Roesch J, et al. Persistence and recurrence of vesicoureteric reflux in children after endoscopic therapy – implications of a risk-adapted follow-up. https://doi.org/10.5173/ceju.2015.560>
<PubMed>
16. Transl Pediatr 2016; 5: 282–90.
< M, Esposito C, Escolino M, et al. Treatment of vesico-ureteral reflux in infants and children using endoscopic approaches. https://doi.org/10.21037/tp.2016.10.04>
<PubMed>
17. J Pediatr Urol 2018; 14: 268.e1–5.
< DA, Ludwig WW, Jayman JR, Akhavan A. The effect of prior endoscopic correction of vesicoureteral reflux on open ureteral reimplantation: Surgical outcomes and costs. https://doi.org/10.1016/j.jpurol.2018.01.023>
18. J Urol 2009; 181: 1869–74.
< EK, Gatti JM, Demaro RT, Murphy JP. Long-term follow-up of dextranomer/hyaluronic acid injection for vesicoureteral reflux: late failure warrants continued follow up. https://doi.org/10.1016/j.juro.2008.12.005>
19. Korean J Urol 2015; 56: 398–404.
< HJ, Im YJ, Lee YS, Kim MJ, Han SW. Is a secondary procedure necessary in every case of failed endoscopic treatment for vesicoureteral reflux? https://doi.org/10.4111/kju.2015.56.5.398>
<PubMed>
20. J Urol 2008; 180: 1601–3.
< B, Natsheh A, Fadeev D, Shenfeld OZ, Farkas A. Unilateral vesicoureteral reflux warranting routine bilateral endoscopic correction. https://doi.org/10.1016/j.juro.2008.03.095>
21. Scand J Urol 2014; 48: 565–70.
< Y, Gulmez H, Güntekin E, Baykara M, Yucel S. Retrospective study of endoscopic treatment in children with primary vesicoureteral reflux and multivariate analysis of factors for failure. https://doi.org/10.3109/21681805.2014.938695>
22. J Pediatr Urol 2013; 9: 1192–7.
< ST, Sung J, Skoog SJ. Endoscopic treatment for vesicoureteral reflux: how important is technique? https://doi.org/10.1016/j.jpurol.2013.05.002>
23. BJU Int 2004; 94: 120–2.
< A, Serrano AJ, Magdalena JR, et al. The use of neural networks for predicting the result of endoscopic treatment for vesico- ureteric reflux. https://doi.org/10.1111/j.1464-410X.2004.04912.x>
24. Indian J Urol 2009; 25: 34–39.
< G. Endoscopic treatment of vesicoureteral reflux: Current status. https://doi.org/10.4103/0970-1591.45534>
<PubMed>
25. J Urol 2007; 178: 1702–5.
< JC, Reinberg Y, Ashley RA, et al. Multivariate comparison of the efficacy of intraureteral versus subtrigonal techniques of dextranomer/ hyaluronic acid injection. https://doi.org/10.1016/j.juro.2007.03.174>
26. J Urol 2004; 171: 2413–6.
< AJ, Perez-Brayfield M, Smith EA, Scherz HC. The modified sting procedure to correct vesicoureteral reflux: Improved results with submucosal implantation within the intramural ureter. https://doi.org/10.1097/01.ju.0000127754.79866.7f>
27. J Pediatr Surg 2016; 51: 2015–20.
< TL, Chen Y, Nah SA, Ong CC, Jacobsen A, Low Y. STING versus HIT technique of endoscopic treatment for vesicoureteral reflux: A systematic review and meta-analysis. https://doi.org/10.1016/j.jpedsurg.2016.09.028>
28. Korean J Urol 2014; 55: 615–9.
< OR, Yalçınkaya F, Altuğ U, Sertçelik N, Demirel F. Does the Modified STING Method Increase the Success Rate in the Management of Moderate or High-Grade Reflux? https://doi.org/10.4111/kju.2014.55.9.615>
<PubMed>
29. J Urol 2007; 177: 1505–9.
< S, Gupta A, Snodgrass W. Multivariate analysis of factors predicting success with dextranomer/hyaluronic acid injection for vesicoureteral reflux. https://doi.org/10.1016/j.juro.2006.11.077>
30. J Urol 2008; 180: 1589–92.
< A, Snodgrass W. Intra-orifice versus hydrodistension implantation technique in dextranomer/hyaluronic acid injection for vesicoureteral reflux. https://doi.org/10.1016/j.juro.2008.04.073>
31. Adv Urol 2008; 513854: 1–7.
< WH, Scherz HC, Kirsch AJ. Endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children. https://doi.org/10.1155/2008/513854>
<PubMed>
32. Eur Urol 2002; 42: 598–606.
< B, Puri P. Endoscopic management of vesicoureteral reflux: does it stand the test of time? https://doi.org/10.1016/S0302-2838(02)00447-5>
33. Actas Urol Esp 2018; 42: 331–7.
< S, Gómez-Fraile A, Carrillo-Arroyo I, et al. Factors involved in the late failure of endoscopic treatment of vesicoureteral reflux. https://doi.org/10.1016/j.acuro.2017.11.006>
34. J Ped Urol 2019; 15: 484–90.
< B, McAndrew F, Corbett H. A review of novel STING bulking agents. https://doi.org/10.1016/j.jpurol.2019.08.018>
35. J Urol 2010; 183: 714–7.
< M, Ruiz E, Denes E, et al. New tissue bulking agent (polyacrylate polyalcohol) for treating vesicoureteral reflux: Preliminary results in children. https://doi.org/10.1016/j.juro.2009.10.047>
36. Urol J 2019; 16: 174–9.
F, Omidi I, Haghdani S, Hatef Khorrami M, Izadpanahi MH, Mohammadi Sichani M. A comparison between dextranomer/ hyaluronic acid and polyacrylate polyalcohol copolymer as bulking agents for treating primary vesicoureteral reflux.
37. J Pediatr Urol 2016; 12: 256. e1–4.
< S, Krzemien G, Szmigielska A, Bombinski P, Brzewski M, Dudek-Warchol T. Comparison of results of endoscopic correction of vesicoureteral reflux in children using two bulking substances: Dextranomer/hyaluronic acid copolymer (Deflux) versus polyacrylate- polyalcohol copolymer (Vantris). https://doi.org/10.1016/j.jpurol.2016.04.006>
38. Int Braz J Urol 2016; 42: 514–20.
< H, Avlan D, Bahadir GB, Delibaş A, Nayci A. The outcomes of two different bulking agents (dextranomer hyaluronic acid copolymer and polyacrylate-polyalcohol copolymer) in the treatment of primary vesico-ureteral reflux. https://doi.org/10.1590/S1677-5538.IBJU.2015.0274>
<PubMed>
39. J Pediatr Surg 2016; 51: 1496–1500.
< SC, User IR, Kılıc BD, Akçaer V, Ceylan H, Ozokutan BH. The comparison of dextranomer/hyaluronic acid and polyacrylate-polyalcohol copolymers in endoscopic treatment of vesicoureteral reflux. https://doi.org/10.1016/j.jpedsurg.2016.02.092>
40. J Pediatr Surg 2016; 51: 1711–5.
< C. Endoscopic treatment of grades IV and V vesicoureteral reflux with two bulking substances: Dextranomer hyaluronic acid copolymer versus polyacrylate polyalcohol copolymer in children. https://doi.org/10.1016/j.jpedsurg.2016.03.013>
41. Urology 2014; 84: 1188–93.
< A, Yıldırım H, Özkan KU, Uçan B, Karkıner A, Hoşgör M. Late ureteral obstruction after endoscopic treatment of vesicoureteral reflux with polyacrylate polyalcohol copolymer. https://doi.org/10.1016/j.urology.2014.07.030>
42. Int Urol Nephrol 2017; 49: 747–52.
< AM, Sabetkish S, Khorramirouz R, Sabetkish N. Comparison of histopathological characteristics of polyacrylate polyalcohol copolymer with dextranomer/hyaluronic acid after injection beneath the bladder mucosa layer: a rabbit model. https://doi.org/10.1007/s11255-017-1540-z>
43. Cent European J Urol 2017; 70: 314–9.
S, Krzemien G, Szmigielska A, Bombinski P, Τoth Κ, Dudek-Warchol T. Endoscopic correction of vesicoureteral reflux in children using polyacrylate-polyalcohol copolymer (Vantris): 5-years of prospective follow-up.
44. H Adv Biomed Res 2013; 2: 1.
F, Shahdoost AA, Zargham M, Tadayon F, Joozdani RH, Arezegar. The influence of ureteral orifice configuration on the success rate of endoscopic treatment of vesicoureteral reflux.
45. J Korean Med Sci 2018; 33: e240.
< W, Nam W, Lee C, et al. Long-term Outcomes of Endoscopic Anti- reflux Surgery in Pediatric Patients with Vesicoureteral Reflux: Urinary Tract Infection, Renal Scarring, and Predictive Factors for Success. https://doi.org/10.3346/jkms.2018.33.e240>
<PubMed>
46. Pediatr Surg Int 2007; 23: 585–9.
< U, Cakan M, Yilmaz S, Yalçinkaya F. Are there predictive factors for the outcome of endoscopic treatment of grade III-V vesicoureteral reflux with dextranomer/hyaluronic acid in children? https://doi.org/10.1007/s00383-007-1881-2>
47. J Pediatr Surg 2017; 52: 1661–5.
< E, Sergio M, Casuccio A, Salerno S, Cimador M. Intraoperative ultrasound-assisted approach for endoscopic treatment of vesicoureteral reflux in children. https://doi.org/10.1016/j.jpedsurg.2017.04.004>
48. J Urol 2008; 179: 1118–20.
< LS. The role of intraoperative cystography following the injection of dextranomer/hyaluronic acid copolymer. https://doi.org/10.1016/j.juro.2007.10.087>
49. J Pediatr Urol 2014; 10: 831–4.
< PJ, Reed F, Ovalle A, et al. Intraoperative cystography pre- and post-endoscopic treatment for vesicoureteral reflux: guaranteed success? https://doi.org/10.1016/j.jpurol.2014.02.002>
50. Pediatr Clin North Am 2012; 59: 819–34.
< FF, Tanno FY, Nguyen HT. Current options in the management of primary vesicoureteral reflux in children. https://doi.org/10.1016/j.pcl.2012.05.012>
51. Roupakias S, Sinopidis X, Spyridakis I, Karatza A, Varvarigou A, Tsikopoulos G. The impact of our acquired experience on endoscopic injection treatment outcomes of vesicoureteral reflux during the first ten years of practice. J Renal Inj Prev 2021; In press (www.http://www.journalrip.com/Inpress).
52. J Urol 2003; 170: 211–5.
< AJ, Perez-Brayfield MR, Scherz HC. Minimally invasive treatment of vesicoureteral reflux with endoscopic injection of dextranomer/ hyaluronic acid copolymer: The Children’s Hospitals of Atlanta experience. https://doi.org/10.1097/01.ju.0000072523.43060.a0>
53. J Urol 2004; 172: 1626–8.
< N, Lais A, Nappo S, Caione P. The role of endoscopic treatment of vesicoureteral reflux: a 17-year experience. https://doi.org/10.1097/01.ju.0000138381.75175.b9>
54. J Urol 2006; 176: 1851–5.
< AJ, Pippi Salle JL, Barroso U, et al. What are the most powerful determinants of endoscopic vesicoureteral reflux correction? Multivariate analysis of a single institution experience during 6 years. https://doi.org/10.1016/S0022-5347(06)00599-4>
55. J Pediatr Urol 2020; 16: 328.e1–9.
< A, Olafsdottir T, Sköldenberg E, Barker G, Stenberg A, Läckgren G. Proprietary non-animal stabilized hyaluronic acid/dextranomer gel (NASHA/Dx) for endoscopic treatment of grade IV vesicoureteral reflux: Long-term observational study. https://doi.org/10.1016/j.jpurol.2020.04.008>
56. Pediatrics 2010; 125: 1010–9.
< JC, Inman BA, Reinberg Y. Dextranomer/hyaluronic acid for pediatric vesicoureteral reflux: systematic review. https://doi.org/10.1542/peds.2009-2225>
57. J Urol 2006; 175: 716–22.
< JS, Diaz M, Caldamone AA, et al. Endoscopic therapy for vesicoureteral reflux: a meta-analysis. I. Reflux resolution and urinary tract infection. https://doi.org/10.1016/S0022-5347(05)00210-7>
58. Urology 2010; 76: 195–8.
< JC, Reinberg Y. Predicting success in the endoscopic management of pediatric vesicoureteral reflux. https://doi.org/10.1016/j.urology.2009.09.017>
59. Urol Int 2008; 81: 41–6.
< M, Ciftci AO, Senocak ME, Tanyel FC, Buyukpamukcu N. Endoscopic Treatment of Vesicoureteral Reflux in Children: Our Experience and Analysis of Factors Affecting Success Rate. https://doi.org/10.1159/000137639>
60. Can J Surg 2012; 55: 301–6.
< M, Todorić J, Budimir D, et al. Endoscopic treatment of vesicoureteral reflux in children with subureteral dextranomer/hyaluronic acid injection: a single-centre, 7-year experience. https://doi.org/10.1503/cjs.003411>
<PubMed>
61. J Urol 2007; 178: 1714–6.
< P, Mohanan N, Menezes M, Colhoun E. Endoscopic treatment of moderate and high grade vesicoureteral reflux in infants using dextranomer/hyaluronic acid. https://doi.org/10.1016/j.juro.2007.03.172>
62. Urology 2017; 110: 196–200.
< S, Gómez-Fraile A, Carrillo-Arroyo I, Tordable-Ojeda C, Cabezalí- Barbancho D. Endoscopic Treatment of Vesicoureteral Reflux in Infants. Can We Do It and Should We Do It? https://doi.org/10.1016/j.urology.2017.08.005>
63. Indian Pediatr 2018; 55: 1046–9.
< KL, Menon P, Samujh R, Mahajan JK, Bawa M, Malik MA, Mittal BR. Endoscopic Management of Vesicoureteral Reflux and Long-term Follow-up. https://doi.org/10.1007/s13312-018-1439-5>
64. J Pediatr Surg 2016; 51: 1366–9.
< E, Pensabene M, Montano V, Casuccio A, Sergio M, Cimador M. Ultrasonographic mound height as predictor of vesicoureteral reflux resolution after endoscopic treatment in children. https://doi.org/10.1016/j.jpedsurg.2016.01.021>
65. Child Kidney Dis 2015; 19: 31–8.
< H, Kim BS, Cheong HI, Cho BS, Kim KM. Long-term Results of Endoscopic Deflux Injection for Vesicoureteral Reflux in Children. https://doi.org/10.3339/chikd.2015.19.1.31>
66. Can Urol Assoc J 2019; 13: 119–24.
PZT, Abdelhalim A, Walia A, Wehbi E, Dave S, Khoury A. Avoiding routine postoperative voiding cystourethrogram: Predicting radiologic success for endoscopically treated vesicoureteral reflux.
67. Urol Ann 2012; 4: 19–23.
R, Olivieri C, Briganti V, et al. Patients with a history of infection and voiding dysfunction are at risk for recurrence after successful endoscopic treatment of vesico ureteral reflux and deserve long-term follow up.
68. J Urol 2012; 188: 1485–9.
< P, Kutasy B, Colhoun E, Hunziker M. Single center experience with endoscopic subureteral dextranomer/hyaluronic acid injection as first line treatment in 1,551 children with intermediate and high grade vesicoureteral reflux. https://doi.org/10.1016/j.juro.2012.02.023>
69. J Pediatr Urol 2016; 12: 255.e1–6.
< JN, Lee SM, Ha YS, et al. VUR timing on VCUG as a predictive factor of VUR resolution after endoscopic therapy. https://doi.org/10.1016/j.jpurol.2016.04.002>
70. Urology 2019; 124: 237–40.
< DS, Cambareri G, Alagiri M, Chiang G. Reflux Timing Is a Predictor of Successful Endoscopic Treatment of Vesicoureteral Reflux. https://doi.org/10.1016/j.urology.2018.09.034>
71. Urology 2015; 85: 896–9.
< T, Sharaf D, AbdelHalim A, Hafez A, Dawaba M. Can distal ureteral diameter predict reflux resolution after endoscopic injection? https://doi.org/10.1016/j.urology.2014.12.021>
72. J Ped Urol 2019; 15: 515.e1–8.
< AD, Hoşgör M, Serdaroğlu E, Sencan A. Can distal ureteral diameter measurement predict primary vesicoureteral reflux clinical outcome and success of endoscopic injection? https://doi.org/10.1016/j.jpurol.2019.07.005>
73. J Pediatr Surg 2017; 52: 2066–9.
< L, Chan IHY, Chung PHY, Lan LCL, Tam PKH, Wong KKY. Endoscopic injection for primary vesicoureteric reflux: Predictors of resolution and long term efficacy. https://doi.org/10.1016/j.jpedsurg.2017.08.033>
74. J Urol 2010; 184: 1134–44.
< CA, Skoog SJ, Arant BS Jr, et al. Summary of the AUA Guideline on Management of Primary Vesicoureteral Reflux in Children. https://doi.org/10.1016/j.juro.2010.05.065>
75. J Urol 2002; 168: 1695–8.
< N, Lais A, Matarazzo E, Nappo S, Patricolo M, Caione P. Influence of voiding dysfunction on the outcome of endoscopic treatment for vesicoureteral reflux. https://doi.org/10.1016/S0022-5347(05)64391-1>
76. J Pediatr Urol 2010; 6: 15–22.
< TW, Reiley EA, Ritch C, Murphy A. The clinical utility and safety of the endoscopic treatment of vesicoureteral reflux in patients with duplex ureters. https://doi.org/10.1016/j.jpurol.2009.05.015>
77. J Urol 2013; 189: 1876–81.
< M, Mohanan N, Puri P. Dextranomer/hyaluronic acid endoscopic injection is effective in the treatment of intermediate and high grade vesicoureteral reflux in patients with complete duplex systems. https://doi.org/10.1016/j.juro.2012.11.048>
78. J Pediatr Urol 2015; 11: 40.e1–5.
< AM, Scherz HC, Filimon E, Leong T, J Kirsch AJ. Is routine voiding cystourethrogram necessary following double hit for primary vesicoureteral reflux? https://doi.org/10.1016/j.jpurol.2014.11.011>
79. J Laparoendosc Adv Surg Tech A 2018; 2: 1408–11.
< L, Paillet P, Minvielle T, et al. Long-Term (>10 Years) results after endoscopic injection therapy for vesicoureteral reflux. https://doi.org/10.1089/lap.2018.0035>
80. Pediatr Urol 2013; 9: 71–6.
< RJF, Dietz HG, Stehr M. Long-term results of endoscopic treatment of vesicoureteral reflux in children: comparison of different bulking agents. https://doi.org/10.1016/j.jpurol.2011.12.004>
81. J Urol 2008; 179: 1966–9.
< A, Gupta A, Snodgrass W. Urinary tract infection following successful dextranomer/hyaluronic acid copolymer for vesicoureteral reflux. https://doi.org/10.1016/j.juro.2008.01.054>
82. J Pediatr 2012; 160: 1015–20.
< M, Mohanan N, D’Asta F, Puri P. Incidence of febrile urinary tract infections in children after successful endoscopic treatment of vesicoureteral reflux: a long-term follow-up. https://doi.org/10.1016/j.jpeds.2011.12.033>