Acta Med. 2021, 64: 193-199

Endoscopic Injection Treatment of Vesicoureteral Reflux in Children: Meeting with the Factors Involved in the Success Rate

Stylianos Roupakiasa,*ID, Xenophon Sinopidisa, Ioannis Spyridakisb, George Tsikopoulosc, Ageliki Karatzad, Anastasia Varvarigoud

aDepartment of Pediatric Surgery, University of Patras Medical School, Patra, Greece
bDepartment of Pediatric Surgery, Aristotelian University of Thessaloniki Medical School, Thessaloniki, Greece
cDepartment of Pediatric Surgery, Hippocrateion General Hospital, Thessaloniki, Greece
dDepartment of Pediatrics, University of Patras Medical School, Patra, Greece

Received June 18, 2021
Accepted October 16, 2021

The challenges and controversies in vesicoureteral reflux intervention guidelines resulted in a more individualized treatment planning. Endoscopic injection therapy is now widely used and is considered preferable, but still remains less successful than ureteral reimplantation. Τhe endoscopic vesicoureteral reflux approach should be risk-adapted to current knowledge, so more experience and longer-term follow-up are needed. The precise of preoperative, intraoperative, and postoperative factors that affecting endoscopic injection therapy success rates and outcome have not yet been clearly determined. The aim of this study was to investigate these associated factors. Although the reflux grade is the most well-known factor that can affect the success of the procedure, there is no agreement on which factors are the most influential for the efficacy of endoscopic reflux treatment. So, we carried out a broad review of published papers on this topic, and we presented all the potential predictive variables of endoscopic reflux resolution in children.


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