Acta Med. 2021, 64: 50-54

Hirata’s Disease: Rare Cause of Hypoglycaemia in Caucasian Male

Kateřina Žibřidová, Barbora Havlínová, Eliška Svobodová, Pavel Žák, Jan Čáp, Filip Gabalec

4th Department of Internal Medicine, University Hospital and Faculty of Medicine Hradec Králové, Charles University, Hradec Králové, Czech Republic

Received October 14, 2020
Accepted December 21, 2020

Insulin autoimmune syndrome or Hirata’s disease is an extremely rare condition leading to hypoglycaemia of variable severity due to autoantibodies against insulin. We present the first case documented in the Czech Republic.


This publication was supported by grant nr. NV19-01-00435, the Ministry of Health of the Czech Republic.


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