Acta Med. 2020, 63: 145-149

Recurrent Aphthous Stomatitis in Children: A Practical Guideline for Paediatric Practitioners

Romana KoberováaID, Vlasta MerglovábID, Vladimíra RadochováaID

aDepartment of Dentistry, Faculty of Medicine in Hradec Králové, Charles University, and University Hospital in Hradec Králové, Czech Republic
bDepartment of Dentistry, Faculty of Medicine, Charles University and University Hospital in Pilsen, Czech Republic

Received June 5, 2020
Accepted July 30, 2020

Recurrent aphthous stomatitis (RAS) is the most common chronic oral mucosal lesion affecting up to 25% of the population. The diagnosis is based on well-defined clinical characteristics, but the precise aetiology and pathogenesis remain unclear. The treatment of RAS should be based on the identification and control of possible predisposing factors. A wide range of topical medicaments is available as antiseptics, anti-inflammatory drugs and corticosteroids. The systemic treatment is indicated in patients with continuous and aggressive manifestation, which is extremely rare in children. The present article provides a review of the current concept and knowledge of the aetiology, pathogenesis, and management of RAS in the paediatric population.


The work was supported by the project PROGRES Q29 (Charles University) and by the Czech Health Research Council, Ministry of Health of the Czech Republic and MH CZ – DRO (UHHK, 00179906).


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