Acta Med. 2017, 60: 71-75

https://doi.org/10.14712/18059694.2017.96

Inflammatory Biomarkers and Liver Histopathology in Non-Uremic and Uremic Chronic Hepatitis C Patients

Bengu Tatara, Sukran Kosea, Emel Palab, Erhan Tatarc

aUniversity of Health Science, Izmir Tepecik Education and Research Hospital, Clinic of Infectious Diseases and Clinical Microbiology, Izmir, Turkey
bUniversity of Health Science, Izmir Tepecik Education and Research Hospital, Pathology, Izmir, Turkey
cUniversity of Health Science, Izmir Bozyaka Education and Research Hospital, Department of Nephrology, Izmir, Turkey

Received November 11, 2016
Accepted July 31, 2017

References

1. Freeman AJ, Dore GJ, Law MG, et al. Estimating progression to cirrhosis in chronic hepatitis C virus infection. Hepatology 2001; 34: 809–816. <https://doi.org/10.1053/jhep.2001.27831>
2. Lavanchy D. The global burden of hepatitis C. Liver Int 2009; 29(Suppl 19): 74–81. <https://doi.org/10.1111/j.1478-3231.2008.01934.x>
3. Williams IT, Bell BP, Kuhnert W, Alter MJ. Incidence and transmission patterns of acute hepatitis C in the United States, 1982–2006. Arch Intern Med 2011; 171: 242–8. <https://doi.org/10.1001/archinternmed.2010.511>
4. Calvaruso V, Craxi A. 2011 Europian Association of THA Study of Liver hepatitis C virus clinical practice guidelines. Liver Int 2012; 32(Suppl 1): 2–8. <https://doi.org/10.1111/j.1478-3231.2011.02703.x>
5. Marinaki S, Boletis JN, Sakellariou S, Delladetsima IK. Hepatitis C in hemodialysis patients. World J Hepatol 2015; 7: 548–58. <https://doi.org/10.4254/wjh.v7.i3.548> <PubMed>
6. Strassburg CP, Manns MP. Approaches to liver biopsy techniques – revisited. Semin Liver Dis 2006; 26: 318–27. <https://doi.org/10.1055/s-2006-951599>
7. Sebastiani G, Alberti A. How far is noninvasive assessment of liver fibrosis from replacing liver biopsy in hepatitis C? J Viral Hepat 2012; 19(Suppl 1): 18–32. <https://doi.org/10.1111/j.1365-2893.2011.01518.x>
8. Gremion C, Cerny A. Hepatitis C virus and the immune system: a concise review. Rev Med Virol 2005; 15: 235–68. <https://doi.org/10.1002/rmv.466>
9. Curry MP, Golden-mason L, Nolan N, et al. Expansion of peripheral blood CD5+ B cells is associated with mild disease in chronic C virus infection. J Hepatol 2000; 32: 121–5. <https://doi.org/10.1016/S0168-8278(00)80198-1>
10. Ishii S, Koziel MJ. Immune responses during acute and chronic infection with hepatitis C virus. Clin Immunol 2008; 128: 133–47. <https://doi.org/10.1016/j.clim.2008.03.525> <PubMed>
11. Bhat T, Teli S, Rijal J, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Rev Cardiovasc Ther 2013; 11: 55–9. <https://doi.org/10.1586/erc.12.159>
12. Tatar E, Mirili C, Isikyakar T, et al. The association of neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio with clinical outcomes in geriatric patients with stage 3–5 chronic kidney disease. Acta Clin Belg 2016; 71: 221–6. <https://doi.org/10.1080/17843286.2016.1159797>
13. Ayça B, Akin F, Celik O, et al. Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention. Platelets 2015; 26: 638–44. <https://doi.org/10.3109/09537104.2014.968117>
14. Johansen JS. Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer. Dan Med Bull 2006; 53: 172–209.
15. Amorim TG, Staub GJ, Lazzarotto C, et al. Validation and comparison of simple noninvasive models for the prediction of liver fibrosis in chronic hepatitis C. Ann Hepatol 2012; 11: 855–61.
16. Saitou Y, Shiraki K, Yamanaka Y, et al. Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease. World J Gastroenterol 2005; 11: 476–81. <https://doi.org/10.3748/wjg.v11.i4.476> <PubMed>
17. Schiavon LL, Schiavon JL, Filho RJ, et al. Simple blood tests as noninvasive markers of liver fibrosis in hemodialysis patients with chronic hepatitis C virus infection. Hepatology 2007; 46: 307–14. <https://doi.org/10.1002/hep.21681>
18. Schiavon LL, Narciso-Schiavon JL, Carvalho Filho RJ, et al. Serum levels of YKL-40 and hyaluronic acid as noninvasive markers of liver fibrosis in haemodialysis patients with chronic hepatitis C virus infection. J Viral Hepat 2008; 15: 666–74. <https://doi.org/10.1111/j.1365-2893.2008.00992.x>
19. Berres ML, Papen S, Pauels K, et al. A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40 serum levels in chronic hepatitis C infection. J Hepatol 2009; 50: 370–6. <https://doi.org/10.1016/j.jhep.2008.09.016>
20. Schiavon LL, Carvalho-Filho RJ, Narciso-Schiavon JL, et al. YKL-40 and hyaluronic acid (HA) as noninvasive markers of liver fibrosis in kidney transplant patients with HCV chronic infection. Scand J Gastroenterol 2010; 45: 615–22. <https://doi.org/10.3109/00365521003637203>
21. Maruyama S, Hirayama C, Horie Y, et al. Serum immunoglobulins in patients with chronic hepatitis C: a surrogate marker of disease severity and treatment outcome. Hepatogastroenterology 2007; 54: 493–8.
22. Gonzàlez-Quintela A, Alende MR, Gamallo R, et al. Serum immunoglobulins (IgG, IgA, IgM) in chronic hepatitis C. A comparison with non-cirrhotic alcoholic liver disease. Hepatogastroenterology 2003; 50: 2121–6.
23. Watt K, Uhanova J, Gong Y, Kaita K, Doucette K, Pettigrew N, et al. Serum immunoglobulins predict the extent of hepatic fibrosis in patients with chronic hepatitis C virus infection. J Viral Hepat 2004; 11: 251–6. <https://doi.org/10.1111/j.1365-2893.2004.00507.x>
24. Schmilovitz-Weiss H, Cohen M, Pappo O, et al. Serum globulin levels in predicting the extent of hepatic fibrosis in patients with recurrent post-transplant hepatitis C infection. Clin Transplant 2007; 21: 391–7. <https://doi.org/10.1111/j.1399-0012.2007.00657.x>
25. Kuo MT, Hu TH, Lu SN, et al. Neutrophil-to-lymphocyte ratio as a predictor of response to peginterferon plus ribavirin therapy for chronic hepatitis C. Dis Markers 2014; 2014: 462958. <https://doi.org/10.1155/2014/462958> <PubMed>
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