Acta Med. 2016, 59: 67-69

A rare case of Ganglioneuroblastoma Encapsulated in Pheochromocytoma

Nathália Vieira Sousaa, Luísa Coelho Marques de Oliveiraa, Paulo José Oliveira Corteza, Vitor Engrácia Valentib, David Mathew Garnerc, Roseane de Souza Candido Iruleguia, Dalmo Antônio Ribeiro Moreiraa,d

aFaculdade de Medicina de Itajubá, Av. Renó Júnior, 368 – São Vicente, Itajubá, MG, Brazil
bPrograma de Pós-Graduação em Fisioterapia, Faculdade de Ciências e Tecnologia, UNESP, Rua Roberto Simonsen, 305, Presidente Prudente, SP, Brazil
cDepartment of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom
dInstituto Dante Pazzanese de Cardiologia, Av. Dr. Dante Pazzanese, 500, São Paulo, SP, Brazil

Received October 16, 2015
Accepted March 2, 2016

Pheochromocytoma and Ganglioneuroblastoma are separate diseases and a rare combination in which the diagnosis can only be confirmed by pathological examination after tumor excision. We reported here a case of ganglioneuroblastoma encapsulated in pheochromocytoma. The patient is a woman, 73 years old, hypertensive, with hypothyroidism, associated for 15 years with hypercholesterolemia and hypertriglyceridemia, which had frequent complaints of low back pain. She underwent magnetic resonance and the findings were consistent with the diagnosis of pheochromocytoma. After surgery, anatomic, pathologic and immunohistochemistry analysis confirmed the diagnosis of pheochromocytoma composed by small ganglioneuroblastoma representation with the identification of small focus of infiltration of the adrenal capsule and adipose tissue by pheochromocytoma. This rare association can instigate the discussion of methods of diagnosis, more effective and more appropriate treatments for each patient.


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