Acta Med. 2014, 57: 112-118
https://doi.org/10.14712/18059694.2014.49
Investigation of Dose-Related Effects of Carnosine on Anxiety with Sympathetic Skin Response and T-maze
References
1. T, Gerlach AL, Rist F. Superior perception of phasic physiological arousal and the detrimental consequences of the conviction to be aroused on worrying and metacognitions in GAD. J Abnorm Psychol 2008; 117: 193–205.
<https://doi.org/10.1037/0021-843X.117.1.193>
2. MA, Rubtsov AM. Histidine-containing dipeptides as endogenous regulators of the activity of sarcoplasmic reticulum Ca-release channels. BBA Biomembranes 1997; 1324: 142–150.
<https://doi.org/10.1016/S0005-2736(96)00216-7>
3. AA, Severin SE. The histidine-containing dipeptides, carnosine and anserine: distribution, properties and biological significance. Adv Enzyme Regul 1990; 30: 175–194.
<https://doi.org/10.1016/0065-2571(90)90017-V>
4. MM, Codispoti M, Cuthbert BN, Lang PJ. Emotion and motivation I: defensive and appetitive reactions in picture processing. Emotion 2001; 1: 276–298.
<https://doi.org/10.1037/1528-3542.1.3.276>
5. E, Moya-Albiol L, González-Bono E, Salvador A, Ricarte J, Gómez-Amor J. Gender differences in cardiovascular and electrodermal responses to public speaking task: the role of anxiety and mood states. Inter J Psychophysiol 2001; 42: 253–264.
<https://doi.org/10.1016/S0167-8760(01)00147-7>
6. LV, Formazuyk VE, Sergienko VI. The anti-oxidative properties of carnosine and other drugs. Biochem Int 1990; 20: 1097–1103.
7. CL. The significance of carnosine and anserine in striated skeletal muscle. Arch Biochem Biophysiol 1960; 89: 303–308.
<https://doi.org/10.1016/0003-9861(60)90059-X>
8. Dawson ME, Schell AM, Filion DL, Berntson GG. The Electrodermal System. Handbook of Psychophysiology. Third edition. New York: Cambridge University Press 2007, p. 159–81.
9. A, Treit D. Dorsal and ventral hippocampal cholinergic systems modulate anxiety in the plus-maze and shock-probe tests. Brain Res 2002; 949: 60–70.
<https://doi.org/10.1016/S0006-8993(02)02965-7>
10. N, Keloglan S, Bitiktas S, Cug S. The effects of the enriched environment on sympathetic skin response in pentylenetetrazol-kindled rats. Biomed Environ Sci 2013 May; 26(5): 394–7.
11. N, Yüksek A, Sizer A, Alay M. Arousal and continuous attention during Ramadan intermittent fasting. J Basic Clin Physiol Pharmacol 2007; 18: 315–322.
12. N. Dose-related anxiogenic effect of glycine in the elevated plus maze and in electrodermal activity. J Basic Clin Physiol Pharmacol 2007; 18: 141–147.
13. N, Özesmi Ç. Assessment of the dose-dependent effect of tryptophan on anxiety with electrodermal activity and elevated plus maze test in mice. Bulletin of Clinical Psychopharmacology 2007; 17: 74–79.
14. M, Harris R. Influence of oral beta-alanine and L-histidine supplementation on the carnosine content of the gluteus medius. Equine Vet J Suppl 1999; 30: 499–504.
<https://doi.org/10.1111/j.2042-3306.1999.tb05273.x>
15. Edelberg R. Electrical activity of the skin: Its measurement and uses in psychophysiology. In: Greenfield NS., Sternbach RS (Eds), Handbook of Psychophysiology. New York: Holt, Rinehart and Winston 1967, p. 367–418.
16. DW, Fisher H. Histamine synthesis, imidazole dipeptides, and wound healing. Surgery 1982; 91: 430–434.
17. Ganong WF. Review of medical physiology. 22nd edition. New York: Lange Medical Books/McGraw-Hill 2005, p. 301–302.
18. SE, Sinclair AJ. Carnosine; physiological properties and therapeutic potential. Age Ageing 2000; 29: 207–210.
<https://doi.org/10.1093/ageing/29.3.207>
19. AM, Cardenas FP, Morato S. The effects of pentylenetetrazol, chlordiazepoxide and caffeine in rats tested in the elevated plus-maze depend on the experimental illumination. Behav Brain Res 2011; 217: 171–177.
<https://doi.org/10.1016/j.bbr.2010.09.032>
20. G, Moreau JL, Jenk F, Martin JR, Mislin R. Some critical determinants of the behaviour of rats in the elevated plus-maze. Behav Processes 1993; 29: 37–48.
<https://doi.org/10.1016/0376-6357(93)90026-N>
21. AR. Could carnosine or related structures suppress Alzheimer’s Disease? Alzheimers Dis 2007; 11: 229–240.
<https://doi.org/10.3233/JAD-2007-11210>
22. Y, Shen J, Fujisaki Y. Effects of l-carnosine on splenic sympathetic nerve activity and tumor proliferation. Neurosci Lett 2012; 21: 510.
23. D, Makatsori A, Duncko R, Moncek F, Jakubek M. High trait anxiety in healthy subjects is associated with low neuroendocrine activity during psychosocial stress. Prog. Neuropsychopharmacol Biol Psychiatry 2004; 28: 1331–1336.
<https://doi.org/10.1016/j.pnpbp.2004.08.005>
24. CL, Yang LX, Wu XH. Effects of carnosıne on amygdaloıd-kindled seizures in Sprague–Dawley rats. Neuroscience 2005; 135: 939–947.
<https://doi.org/10.1016/j.neuroscience.2005.06.066>
25. CL, Sakurai E, Kiso Y, Luo JH, Yanai K, Chen Z. Influence of low dietary histamine on seizure development of chemical kindling induced by pentylenetetrazol in rats. Acta Pharmacol Sin 2005; 26: 423–427.
<https://doi.org/10.1111/j.1745-7254.2005.00097.x>
26. P, Aldstadt J. Effects of carnosine and anserine on muscle and non-muscle phosphorylases. Comp Biochem Physiol 1984; 78: 331–333.
27. KV, Krishna DR, Palit G. Histaminergic H1 receptors mediate l-histidine-induced anxiety in elevated plus-maze test in mice. Behav Pharmacol 2007; 18: 213–217.
<https://doi.org/10.1097/FBP.0b013e328157f450>
28. RG. Etiologically based animal models of anxiety disorders. Pharmacol Ther 1990; 46: 321–340.
<https://doi.org/10.1016/0163-7258(90)90021-S>
29. N, McMurray J. Synergism of histidyl dipeptides as antioxidants. J Molec Cell Cardiol 1991; 23: 1205–1207.
<https://doi.org/10.1016/0022-2828(91)90077-Y>
30. R, Quermonne MA, Raoul J, Nammathao B, Smida A. Skin Conductance Reaction (SCR)-Habituation Test, a tool to detect anxiolytic activity. Its justification by the correlation between SCR-Habituation Test activities and specific binding potencies in benzodiazepines. Prog. Neuropsychopharmacol. Biol Psychiat 1985; 9: 387–391.
<https://doi.org/10.1016/0278-5846(85)90191-5>
31. S, Hirano S, Ohsawa M, Kamei J. Chlorpheniramine exerts anxiolytic-like effects and activates prefrontal 5-HT systems in mice. Psychopharmacology 1993; 213: 441–452.
<https://doi.org/10.1007/s00213-009-1695-0>
32. T, Furuse M. The impact of taurine- and beta-alanine-supplemented diets on behavioral and neurochemical parameters in mice: antidepressant versus anxiolytic-like effects. Amino Acids 2010; 39: 427–34.
<https://doi.org/10.1007/s00726-009-0458-x>
33. L, Dehaene S, Cohen L, Habert MO, Guichart Gomez E, Galanaud D. Effortless control: executive attention and conscious feeling of mental effort are dissociable. Neuropsychologia 2005; 43: 1318–1328.
<https://doi.org/10.1016/j.neuropsychologia.2004.11.024>
34. K, Tanida M, Niijima A, Tsuruoka N, Kiso Y, Horii Y. Role of L-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine. Amino Acids 2012; 43: 97–109.
<https://doi.org/10.1007/s00726-012-1251-9>
35. K, Niijima A, Yamano T, Otani H, Okumura N, Tsuruoka N, Nakai M, Kiso Y. Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves. Exp Biol Med 2003; 228: 1138–1145.
<https://doi.org/10.1177/153537020322801007>
36. M, Eriksson C, Schultzberg M. Inflammatory mechanisms associated with brain damage induced by kainic acid with special reference to the interleukin-1 system. J Cell Mol Med 2003; 7: 127–140.
<https://doi.org/10.1111/j.1582-4934.2003.tb00211.x>
<PubMed>
37. S, Chopin P, File SE, Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 1985; 14: 149–167.
<https://doi.org/10.1016/0165-0270(85)90031-7>
38. S, File SE. Anxiolytic and anxiogenic drug effects in exploratory activity in an elevated plus-maze. A novel test of anxiety in the rat. Pharmacol Biochem Behav 1986; 24: 525–529.
<https://doi.org/10.1016/0091-3057(86)90552-6>
39. H, Tran MH, Lamberti C, Fischer H, Kraus M, Grass K. Histaminergic neurons modulate acetylcholine release in the ventral striatum: role of H1 and H2 histamine receptors. Naunyn. Schmiedebergs. Arch Pharmacol 1999; 360: 552–557.
<https://doi.org/10.1007/s002109900098>
40. C, Knoche A, Hasenohrl RU, Huston JP. The H1- and H2-histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes. Neuropharmacology 1998; 37: 1019–1032.
<https://doi.org/10.1016/S0028-3908(98)00087-2>
41. MA, Nammathao B, Louchahi-Raoul J, Marcy R. Skin conductance reaction–habituation test, an elementary model of anxiety as a tool to assess anxiogenic activities of some drugs. Prog. Neuropsychopharmacol. Biol Psychiatry 1993; 17: 311–318.
<https://doi.org/10.1016/0278-5846(93)90050-3>
42. KR, Kishi MS, Canto-de-Souza A, Mattioli R. H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing. Braz J Med Biol Res 2013; 46: 440–446.
<https://doi.org/10.1590/1414-431X20132770>
<PubMed>
43. J, Yao JF, Tanida M, Nagai K. Regulation of sympathetic nerve activity by L-carnosine in mammalian white adipose tissue. Neurosci Lett 2008; 441: 100–104.
<https://doi.org/10.1016/j.neulet.2008.06.027>
44. TJ. Self-discrepancies in clinical depression and social phobia: cognitive structures that underlie emotional disorders? J Abnorm. Psychol 1989; 98: 14–22.
<https://doi.org/10.1037/0021-843X.98.1.14>
45. C, Dolu N, Ozesmi C, Sahin O, Ulgen A. The relation between skin conductance level and plus-maze behavior in male mice. Physiol Behav 1998; 64: 573–576.
<https://doi.org/10.1016/S0031-9384(98)00075-4>
46. C, Dolu N. Electrophysiological evidence of biphasic action of carnosine on long-term potentiation in urethane-anesthetized rats. Neuropeptides 2011; 45: 77–81.
<https://doi.org/10.1016/j.npep.2010.11.004>
47. M, Niijima A. Dose-dependent effects of L-carnosine on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats. Am J Physiol Regul Integr Comp Physiol 2005; 288: 447–455.
<https://doi.org/10.1152/ajpregu.00275.2004>
48. M, Gotoh H, Taniguchi H, Otani H, Shen J, Nakamura T. Effects of central injection of L-carnosine on sympathetic nerve activity innervating brown adipose tissue and body temperature in rats. Regul Pept 2007; 144: 62–71.
<https://doi.org/10.1016/j.regpep.2007.06.001>
49. T, Kubo Y, Akanuma SI, Hosoya KI. β-Alanine and L-histidine transport across the inner blood-retinal barrier: potential involvement in L-carnosine supply. Exp Eye Res 2013; 113: 135–142.
<https://doi.org/10.1016/j.exer.2013.06.002>
50. LM, Phillips ML, Brammer MJ, Skerrett D, Lagopoulos J. Arousal Dissociates Amygdala and Hippocampal Fear Responses: Evidence from Simultaneous fMRI and Skin Conductance Recording. NeuroImage 2001; 14: 1070–1079.
<https://doi.org/10.1006/nimg.2001.0904>
51. FS, Gibbs TT, Farb DH. Dual activation of GABAA and glycine receptors by beta-alanine: inverse modulation by progesterone and 5 alpha-pregnan-3 alpha-ol-20-one. Eur J Pharmacol 1993; 246: 239–246.
<https://doi.org/10.1016/0922-4106(93)90037-A>
52. CJ, Acosta-Rua AJ, Rossi HL, Neubert JK. Sex Differences in Thermal Pain Sensitivity and Sympathetic Reactivity for Two Strains of Rat. J Pain 2008; 9: 739–749.
<https://doi.org/10.1016/j.jpain.2008.03.008>
<PubMed>
53. MR, Nasehi M, Piri M, Bina P. Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice. Pharmacol Biochem Behav 2010; 94: 387–396.
<https://doi.org/10.1016/j.pbb.2009.09.021>
