Acta Med. 2014, 57: 21-27


Kumari Ashaa, Suman B. Sharmaa, Archana Singalb, Amitesh Aggarwalc

aUniversity College of Medical Sciences and G.T.B. Hospital, Dilshad Garden, University of Delhi, India: Department of Biochemistry
bUniversity College of Medical Sciences and G.T.B. Hospital, Dilshad Garden, University of Delhi, India: Department of Dermatology
cUniversity College of Medical Sciences and G.T.B. Hospital, Dilshad Garden, University of Delhi, India: Department of Medicine


1. Prodanovich S, Kirsner RS, Kravetz JD, Ma F, Martinez L, Federman DG. Association of psoriasis with coronary artery, cerebrovascular, and peripheral vascular disease and mortality. Arch Dermatol 2009; 145: 700–03. <>
2. Rocha-Pereira P, Santos-Silva A, Rebelo I, et al. Dislipidemia and oxidative stress in mild and in severe psoriasis as a risk for cardiovascular disease. Clin Chim Acta. 2001 Jan; 303(1–2): 33–9. <>
3. Jellinger PS, Smith DA, Mehta AE, et al. American Association of Clinical Endocrinologists Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis. Endocr Pract 2012; 18(1): 1–78. <>
4. Johnston A, Arnadottir S, Gudjonsson JE, et al. Obesity in psoriasis: Leptin and resistin as mediators of cutaneous inflammation. Br J Dermatol 2008; 159: 342–50. <> <PubMed>
5. Fujita Y, Murakami M, Ogawa Y, et al. Leptin inhibits stress-induced apoptosis of T lymphocytes. Clin Exp Immunol 2002; 128: 21–26. <> <PubMed>
6. Aktan F, Rota S, Erdogan BS, et al. A Role of leptin in psoriasis? Turk J Med Sci 2007; 37(3): 135–38.
7. Asanuma Y, Oeser A, Shintani AK, et al. Premature coronary-artery atherosclerosis in systemic lupus erythematosus. N Engl J Med 2003; 349: 2407–15. <>
8. Belibou C, Ancuţa C, Ancuţa E, Filos C, Chirieac R. Carotid intima-media thickness and plaque as surrogate biomarkers of atherosclerosis among consecutive women with systemic lupus erythematosus. Rom J Morphol Embryol 2012; 53: 29–34.
9. Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001; 285: 2486–97.
10. Einhorn D, Reaven GM, Cobin RH, et al. American College of Endocrinology position statement on the insulin resistance syndrome. Endocr Pract 2003; 9: 237–52.
11. Alberti KG, Zimmet P, Shaw J. IDF. Epidemiology Task Force Consensus Group. The metabolic syndrome – a new worldwide definition. Lancet 2005; 366: 1059–62. <>
12. Fredriksson T, Pettersson U. Severe psoriasis-oral therapy with a new retinoid. Dermatologica 1978; 157: 238–44. <>
13. Votila M, Ruoslanti E, Enguall E. Immunology methods. J Immunol Methods 1981; 42: 11–15. <>
14. Huang Y, Bi Y, Wang W, et al. Glycated hemoglobin A1c, fasting plasma glucose, and two-hour postchallenge plasma glucose levels in relation to carotid intima-media thickness in chinese with normal glucose tolerance. J Clin Endocrinol Metab 2011; 96: 1461–65. <>
15. Mok CC, Ko GT, Ho LY, Yu KL, Chan PT, To CH. Prevalence of atherosclerotic risk factors and the metabolic syndrome in patients with chronic inflammatory arthritis. Arthritis Care Res 2011; 63: 195–202. <>
16. Cohen AD, Sherf M, Vidavsky L, Vardy DA, Shapiro J, Meyerovitch J. Association between psoriasis and the metabolic syndrome. A cross-sectional study. Dermatol 2008; 216: 152–55. <>
17. Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol 2006; 55: 829–35. <>
18. Shapiro J, Cohen AD, David M, et al. The association between psoriasis, diabetes mellitus, and atherosclerosis in Israel: a case-control study. J Am Acad Dermatol 2007; 56: 629–34. <>
19. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. J Am Med Assoc 2006; 296: 1735–41. <>
20. Seishima M, Seishima M, Mori S, Noma A. Serum lipid and apolipoprotein levels in patients with psoriasis. Br J Dermatol 1994; 130: 738–42. <>
21. Bajaj DR, Mahesar SM, Devrajani BR, Iqbal MP. Lipid profile in patients with psoriasis presenting at Liaquat University Hospital Hyderabad. J Pak Med Assoc 2009; 59(8): 512–15.
22. Henseler T, Christophers E. Disease concomitance in psoriasis. J Am Acad Dermatol 1995; 32: 982–86. <>
23. Naldi L, Chatenoud L, Linder D, et al. Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case–control study. J Invest Dermatol 2005; 125: 61–67. <>
24. Enany B, El Zohiery AK, Elhilaly R, Badr T. Carotid intima-media thickness and serum leptin in psoriasis. Herz 2012; 37: 527–33. <>
25. Cerman AA, Bozkurt S, Sav A, Tulunay A, Elbasi MO, Ergun T. Serum leptin levels, skin leptin and leptin receptor expression in psoriasis. Br J Dermatol 2008; 159: 820–26. <>
26. Hamminga EA, Lely AJ, Neumann HA, Thio HB. Chronic inflammation in psoriasis and obesity: implication for therapy. Med Hypotheses 2006; 67: 768–73. <>
27. Kimhi O, Caspi D, Bornstein NM, et al. Prevalence and risk factors of atherosclerosis in patients with psoriatic arthritis. Semin Arthritis Rheum 2007; 36: 203–09. <>
28. Gonzalez JC, Llorca J, Amigo DE, Dierssen T, Martin J, Gonzalez GMA. High prevalence of subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors. Arthritis Rheum 2007; 57: 1074–80. <>
29. El-Mongy S, Fathy H, Abdelaziz A, et al. Subclinical atherosclerosis in patients with chronic psoriasis: a potential association. J Eur Acad Dermatol Venereol 2010; 24: 661–66. <>
30. Grobbee DE, Bots ML. Carotid artery intima-media thickness as an indicator of generalized atherosclerosis. J Intern Med 1994; 236: 567–73. <>
31. Tam LS, Shang Q, Li EK, et al. Subclinical carotid atherosclerosis in patients with psoriatic arthritis. Arthritis Rheum 2008; 59: 1322–31. <>
32. Tam LS, Tomlinson B, Chu TT, et al. Cardiovascular risk profile of patients with psoriatic arthritis compared to controls-the role of inflammation. Rheumatol 2008; 47: 718–23. <>
33. Youssef SS, Hosny S, Bakr I, Youssef A. Susceptibility to atherosclerosis in patients with psoriasis and psoriatic arthritis as determined by increased carotid artery intima-media thickness. J Pan-Arab League of Dermatologists 2009; 20: 159–72.
34. Huang F, Yang Z, Xu B, et al. Both serum ApoB and the ApoB/apoA-I ratio are associated with carotid intima-media thickness. PloS ONE 2013; 8(1): e54628. <> <PubMed>
35. Dahlen EM, Lanne T, Engvall J, et al. Carotid intima-media thickness and apoB/apoA-I ratio in middle-aged patients with Type 2 diabetes. Diabet Med 2009; 26: 384–90. <>
36. Doria A, Shoenfeld Y, Wu R, et al. Risk factors for subclinical atherosclerosis in a prospective cohort of patients with systemic lupus erythematosus. Ann Rheum Dis 2003; 62: 1071–77. <> <PubMed>
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