Acta Med. 2013, 56: 89-96

https://doi.org/10.14712/18059694.2014.15

LABORATORY EXAMINATION IN NERVE AGENT INTOXICATION

Jiří Bajgara,b

aUniversity of Defence, Faculty of Military Health Sciences, Hradec Králové, Czech Republic: Department of Toxicology
bUniversity of South Bohemia České Budějovice, Faculty of Social and Health Studies, Czech Republic: Department of Radiology and Toxicology

Diagnosis of nerve agent intoxication is based on anamnestic data, clinical signs and laboratory examination. For acute poisoning, cholinesterase activity in the blood (erythrocyte AChE, plasma/serum BuChE) is sensitive, simple and most frequent laboratory examination performed in biochemical laboratories. Specialized examinations to precise treatment (reactivation test) or to make retrospective diagnosis (fluoride induced reactivation etc.) can be conducted. Other sophisticated methods are available, too.

References

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