Acta Med. 2013, 56: 89-96
LABORATORY EXAMINATION IN NERVE AGENT INTOXICATION
Diagnosis of nerve agent intoxication is based on anamnestic data, clinical signs and laboratory examination. For acute poisoning, cholinesterase activity in the blood (erythrocyte AChE, plasma/serum BuChE) is sensitive, simple and most frequent laboratory examination performed in biochemical laboratories. Specialized examinations to precise treatment (reactivation test) or to make retrospective diagnosis (fluoride induced reactivation etc.) can be conducted. Other sophisticated methods are available, too.
Keywords
Nerve agents, Metabolites, Diagnosis, Blood, Acetylcholinesterase, Erythrocytes, Butyrylcholinesterase, Plasma, Reactivation.
References
Copyright
Published by the Karolinum Press. For permission to use please write to actamedica@lfhk.cuni.cz.