BROWN TUMOR AT THE JAW IN PATIENTS  WITH SECONDARY HYPERPARATHYROIDISM DUE  TO CHRONIC RENAL FAILURE

Pechalova, Petia F.; Poriazova, Elena G.

doi:10.14712/18059694.2014.29

Acta Medica > Archive > 2013, Vol. 56 > Issue 2 > BROWN TUMOR AT THE JAW IN PATIENTS WITH…

Acta Med. 2013, 56: 83-86

https://doi.org/10.14712/18059694.2014.29

BROWN TUMOR AT THE JAW IN PATIENTS WITH SECONDARY HYPERPARATHYROIDISM DUE TO CHRONIC RENAL FAILURE

Petia F. Pechalova^a, Elena G. Poriazova^b

^aMedical University, Plovdiv, Bulgaria: Faculty of Dental Medicine, Department of Maxillo-facial Surgery
^bMedical University, Plovdiv, Bulgaria: Faculty of Medicine, Department of Pathology

Brown tumors are bony lesions caused by rapid osteoclastic activity, which rare involved jaws. Renal osteodystrophy (ROD) is associated with different pathogenetic mechanisms – disorder of calcium-phosphate metabolism, impaired metabolism of vitamin D, increased parathyroid activity that lead to extreme concentrations of parathormone.
The authors report two cases of jaw enlargement in patients received haemodialysis with excessive increase values of alkaline phosphatase and parathormone in serum. The patients were treated surgically with corrective procedures in maxillo-facial area.
ROD of the jaws could be severe complication in dialysis patients with end stage of CKD if no appropriate care aimed at correction or prevention of parathyroid hyperfunction was applied to them.