EFFICACY OF TOPIRAMATE AS ADD-ON THERAPY IN TWO DIFFERENT TYPES OF PROGRESSIVE MYOCLONIC EPILEPSY

Demir, Caner Feyzi; Özdemir, Hasan Hüseyin; Müngen, Bülent

doi:10.14712/18059694.2014.37

Acta Medica > Archive > 2013, Vol. 56 > Issue 1 > EFFICACY OF TOPIRAMATE AS ADD-ON THERAPY…

Acta Med. 2013, 56: 36-38

https://doi.org/10.14712/18059694.2014.37

EFFICACY OF TOPIRAMATE AS ADD-ON THERAPY IN TWO DIFFERENT TYPES OF PROGRESSIVE MYOCLONIC EPILEPSY

Caner Feyzi Demir^a, Hasan Hüseyin Özdemir^b, Bülent Müngen^a

^aDepartment of Neurology, Fırat (Euphrates) University, Elazıg, Turkey
^bBismil State Hospital, Neurology, Diyarbakır, Turkey

The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora’s disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with marked decrease in myoclonic seizure frequency and improvement of quality of life. Topiramate appears to be a useful alternative agent in cases of PME and could be consider for adjunctive therapy.