Acta Med. 2011, 54: 97-101

https://doi.org/10.14712/18059694.2016.28

The Role of Hydrogen Peroxide and Other Reactive Oxygen Species in Wound Healing

Jiří Kanta

Charles University in Prague, Faculty of Medicine in Hradec Králové, Department of Medical Biochemistry, Czech Republic

Received January 12, 2011
Accepted March 18, 2011

Crossref Cited-by Linking

  • Das Monojit, Mondal Susmita, Ghosh Ria, Darbar Soumendra, Roy Lopamudra, Das Anjan Kumar, Pal Debasish, Bhattacharya Siddhartha Sankar, Mallick Asim Kumar, Kundu Jayanta Kumar, Pal Samir Kumar: A study of scarless wound healing through programmed inflammation, proliferation and maturation using a redox balancing nanogel. J Biomedical Materials Res 2024. <https://doi.org/10.1002/jbm.a.37712>
  • Harris B., Wagenaars E.: The influence of pulse repetition frequency on reactive oxygen species production in pulsed He+H2O plasmas at atmospheric pressure. Journal of Applied Physics 2023, 134. <https://doi.org/10.1063/5.0161825>
  • Rai Sanjay, Gupta Tej Pratap, Shaki Omna, Kale Amit: Hydrogen Peroxide: Its Use in an Extensive Acute Wound to Promote Wound Granulation and Infection Control – Is it Better Than Normal Saline?. The International Journal of Lower Extremity Wounds 2023, 22, 563. <https://doi.org/10.1177/15347346211032555>
  • Sudsai Teeratad, Tungcharoen Pattreeya, Tewtrakul Supinya: Wound healing properties of pharmaceutical gel containing isopimarane diterpene isolated from Kaempferia galanga L. Journal of Ethnopharmacology 2022, 289, 115052. <https://doi.org/10.1016/j.jep.2022.115052>
  • Xu Qingqing, Dai Xiaomei, Yang Lele, Liu Xiaojun, Li Yu, Gao Feng: ε-Polylysine-Based Macromolecules with Catalase-Like Activity to Accelerate Wound Healing by Clearing Bacteria and Attenuating Inflammatory Response. ACS Biomater. Sci. Eng. 2022, 8, 5018. <https://doi.org/10.1021/acsbiomaterials.2c00986>
  • Chen Tao, Min Yuanhong, Yang Xiao, Gong Hao, Tian Xiaoying, Liu Li, Hou Yanhua, Fu Wensheng: Designing CoS1.035 Nanoparticles Anchored on N-Doped Carbon Dodecahedron as Dual-Enzyme Mimics for the Colorimetric Detection of H2O2 and Glutathione. ACS Omega 2022, 7, 11135. <https://doi.org/10.1021/acsomega.1c07264>
  • Botchway Benson OA, Okoye Favour C, Chen Yili, Arthur William E, Fang Marong: Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents. Aging and disease 2022, 13, 87. <https://doi.org/10.14336/AD.2021.0616>
  • Casado-Díaz Antonio, La Torre Manuel, Priego-Capote Feliciano, Verdú-Soriano José, Lázaro-Martínez José Luis, Rodríguez-Mañas Leocadio, Berenguer Pérez Miriam, Tunez Isaac: EHO-85: A Multifunctional Amorphous Hydrogel for Wound Healing Containing Olea europaea Leaf Extract: Effects on Wound Microenvironment and Preclinical Evaluation. JCM 2022, 11, 1229. <https://doi.org/10.3390/jcm11051229>
  • Gouarderes Sara, Doumard Layal, Vicendo Patricia, Mingotaud Anne-Françoise, Rols Marie-Pierre, Gibot Laure: Electroporation does not affect human dermal fibroblast proliferation and migration properties directly but indirectly via the secretome. Bioelectrochemistry 2020, 134, 107531. <https://doi.org/10.1016/j.bioelechem.2020.107531>
  • Sannasimuthu Anbazahan, Ramani Madhura, Paray Bilal Ahamad, Pasupuleti Mukesh, Al-Sadoon Mohammad K., Alagumuthu Tamil Selvi, Al-Mfarij Abdul Rahman, Arshad Aziz, Mala Kanchana, Arockiaraj Jesu: Arthrospira platensis transglutaminase derived antioxidant peptide-packed electrospun chitosan/ poly (vinyl alcohol) nanofibrous mat accelerates wound healing, in vitro, via inducing mouse embryonic fibroblast proliferation. Colloids and Surfaces B: Biointerfaces 2020, 193, 111124. <https://doi.org/10.1016/j.colsurfb.2020.111124>
  • Khémiri Ikram, Essghaier Badiaa, Sadfi-Zouaoui Najla, Bitri Lotfi, Gon alves Reggiani Vilela: Antioxidant and Antimicrobial Potentials of Seed Oil from Carthamus tinctorius L. in the Management of Skin Injuries. Oxidative Medicine and Cellular Longevity 2020, 2020, 1. <https://doi.org/10.1155/2020/4103418>
  • Taute Helena, Bester Megan J., Gaspar Anabella R.M.: The dual functionality of antimicrobial peptides Os and Os‐C in human leukocytes. Journal of Peptide Science 2019, 25. <https://doi.org/10.1002/psc.3156>
  • Korschelt Karsten, Tahir Muhammad Nawaz, Tremel Wolfgang: A Step into the Future: Applications of Nanoparticle Enzyme Mimics. Chemistry A European J 2018, 24, 9703. <https://doi.org/10.1002/chem.201800384>
  • Benelli Roberto, Venè Roberta, Ferrari Nicoletta: Prostaglandin-endoperoxide synthase 2 (cyclooxygenase-2), a complex target for colorectal cancer prevention and therapy. Translational Research 2018, 196, 42. <https://doi.org/10.1016/j.trsl.2018.01.003>
  • Sztanke Małgorzata, Kandefer-Szerszeń Martyna, Sztanke Krzysztof: Biologically and chemically important hydrazino-containing imidazolines as antioxidant agents. Free Radical Research 2018, 52, 685. <https://doi.org/10.1080/10715762.2018.1464655>
  • Di Marzo Noemi, Chisci Elisa, Giovannoni Roberto: The Role of Hydrogen Peroxide in Redox-Dependent Signaling: Homeostatic and Pathological Responses in Mammalian Cells. Cells 2018, 7, 156. <https://doi.org/10.3390/cells7100156>
  • Zhu Yuanjun, Zhou Tongliang, Yang Lingfei, Yuan Lan, Liang Lei, Xu Ping: Revelation of the dynamic progression of hypoxia-reoxygenation injury by visualization of the lysosomal hydrogen peroxide. Biochemical and Biophysical Research Communications 2017, 486, 904. <https://doi.org/10.1016/j.bbrc.2017.03.121>
  • Liao Xin, Huang Chao, Zhang Dongyun, Wang Jingjing, Li Jingxia, Jin Honglei, Huang Chuanshu: Mitochondrial Catalase Induces Cells Transformation Through Nucleolin-dependent Cox-2 mRNA Stabilization. Free Radical Biology and Medicine 2017. <https://doi.org/10.1016/j.freeradbiomed.2017.10.387>
  • Seo Seung Beom, Dananjaya S.H.S., Nikapitiya Chamilani, Park Bae Keun, Gooneratne Ravi, Kim Tae-Yoon, Lee Jehee, Kim Cheol-Hee, De Zoysa Mahanama: Silver nanoparticles enhance wound healing in zebrafish (Danio rerio). Fish & Shellfish Immunology 2017, 68, 536. <https://doi.org/10.1016/j.fsi.2017.07.057>
  • Hu Minghan, Korschelt Karsten, Daniel Phillip, Landfester Katharina, Tremel Wolfgang, Bannwarth Markus B.: Fibrous Nanozyme Dressings with Catalase-Like Activity for H2O2 Reduction To Promote Wound Healing. ACS Appl. Mater. Interfaces 2017, 9, 38024. <https://doi.org/10.1021/acsami.7b12212>
  • Dunnill Christopher, Patton Thomas, Brennan James, Barrett John, Dryden Matthew, Cooke Jonathan, Leaper David, Georgopoulos Nikolaos T: Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS‐modulating technologies for augmentation of the healing process. International Wound Journal 2017, 14, 89. <https://doi.org/10.1111/iwj.12557>
  • Rivie A., Martus K., Menon J.: Atmospheric pressure plasma accelerates tail regeneration in tadpoles Xenopus laevis. Eur. Phys. J. Spec. Top. 2017, 226, 2859. <https://doi.org/10.1140/epjst/e2016-60243-3>
  • Prevatto Jessika P., Torres Rafael C., Diaz Bruno L., Silva Patrícia M. R. e, Martins Marco A., Carvalho Vinicius F.: Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary. Oxidative Medicine and Cellular Longevity 2017, 2017, 1. <https://doi.org/10.1155/2017/4156361>
  • Shao Pei-Lin, Liao Jiunn-Der, Wong Tak-Wah, Wang Yi-Cheng, Leu Steve, Yip Hon-Kan, Yousfi Mohammed: Enhancement of Wound Healing by Non-Thermal N2/Ar Micro-Plasma Exposure in Mice with Fractional-CO2-Laser-Induced Wounds. PLoS ONE 2016, 11, e0156699. <https://doi.org/10.1371/journal.pone.0156699>
  • Pietra Daniele, Borghini Alice, Bianucci Anna Maria: In vitro studies of antifibrotic and cytoprotective effects elicited by proto-berberine alkaloids in human dermal fibroblasts. Pharmacological Reports 2015, 67, 1081. <https://doi.org/10.1016/j.pharep.2015.04.001>
  • Nafiu Abdulrazaq Bidemi, Rahman Mohammad Tariqur: Anti-inflammatory and antioxidant properties of unripe papaya extract in an excision wound model. Pharmaceutical Biology 2015, 53, 662. <https://doi.org/10.3109/13880209.2014.936470>
  • Tang Shifu, Yang Li, Tang Xi, Liu Manran: The role of oxidized ATM in the regulation of oxidative stress-induced energy metabolism reprogramming of CAFs. Cancer Letters 2014, 353, 133. <https://doi.org/10.1016/j.canlet.2014.07.028>
  • Cheung Isabella M Y, Mcghee Charles N J, Sherwin Trevor: Beneficial effect of the antioxidant riboflavin on gene expression of extracellular matrix elements, antioxidants and oxidases in keratoconic stromal cells. Clinical and Experimental Optometry 2014, 97, 349. <https://doi.org/10.1111/cxo.12138>
  • Uraga-Tovar D. Italibi, Domínguez-López M. Lilia, Madera-Sandoval Ruth L., Nájera-Martínez Minerva, García-Latorre Ethel, Vega-López Armando: Generation of oxyradicals ( and H2O2), mitochondrial activity and induction of apoptosis of PBMC ofCyprinus carpio carpiotreatedin vivowith halomethanes and with recombinant HSP60 kDa and with LPS ofKlebsiella pneumoniae. Immunopharmacology and Immunotoxicology 2014, 36, 329. <https://doi.org/10.3109/08923973.2014.947034>
  • Colvin Arthur E., Jiang Hui: Increased in vivo stability and functional lifetime of an implantable glucose sensor through platinum catalysis. J Biomedical Materials Res 2013, 101A, 1274. <https://doi.org/10.1002/jbm.a.34424>
  • Vera-Jimenez N.I., Pietretti D., Wiegertjes G.F., Nielsen M.E.: Comparative study of β-glucan induced respiratory burst measured by nitroblue tetrazolium assay and real-time luminol-enhanced chemiluminescence assay in common carp (Cyprinus carpio L.). Fish & Shellfish Immunology 2013, 34, 1216. <https://doi.org/10.1016/j.fsi.2013.02.004>
  • Vera-Jimenez N.I., Nielsen M.E.: Carp head kidney leukocytes display different patterns of oxygen radical production after stimulation with PAMPs and DAMPs. Molecular Immunology 2013, 55, 231. <https://doi.org/10.1016/j.molimm.2013.01.016>
Crossref Cited-by Linking logo