Acta Med. 2007, 50: 203-206

https://doi.org/10.14712/18059694.2017.83

Evaluation of Potency of Known Oximes (Pralidoxime, Trimedoxime, HI-6, Methoxime, Obidoxime) to in vitro Reactivate Acetylcholinesterase Inhibited by Pesticides (Chlorpyrifos and Methylchlorpyrifos and Nerve Agent (Russian VX)

Kamil Musíleka,b, Kamil Kučab,c, Daniel Junb,c

aCharles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Chemistry and Drug Control, Hradec Králové, Czech Republic
bUniversity of Defence, Faculty of Military Health Sciences, Department of Toxicology, Hradec Králové, Czech Republic
cUniversity of Defence, Faculty of Military Health Sciences, Centre of Advanced Studies, Hradec Králové, Czech Republic

Received March 1, 2007
Accepted July 1, 2007

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  • Franklin Matthew C., Rudolph Michael J., Ginter Christopher, Cassidy Michael S., Cheung Jonah: Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins 2016, 84, 1246. <https://doi.org/10.1002/prot.25073>
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