Acta Med. 2007, 50: 171-176
https://doi.org/10.14712/18059694.2017.78
In Vitro Antiproliferative Effects of Sulforaphane on Human Colon Cancer Cell Line SW620
References
1. GL, Adair LS, Galanko JA, Martin CF, Satia JA, Sandler RS. A diet high in fruits and low in meats reduces the risk of colorectal adenomas. J Nutr 2007; 137:999–1004.
<https://doi.org/10.1093/jn/137.4.999>
2. C, Eggleston IM, Hayes JD. Dietary Indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 2001; 61:6120–30.
3. JH, Kristal AR, Stanford JL. Fruit and vegetable intakes and prostate cancer risk. J Natl Cancer Inst 2000; 92:61–68.
<https://doi.org/10.1093/jnci/92.1.61>
4. O, Lee A, Nussenzweig M, Nussenzweig A. H2AX: the histone guardian of the genome. DNA Repair 2004; 3:959–67.
<https://doi.org/10.1016/j.dnarep.2004.03.024>
5. L, Li P, Lumeau S, Cassar G, Dupont MA, Chevolleau S, Gasc N, Tulliez J, Terce F. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res 2000; 60:1426–33.
6. AV, Al-janobi A, Smith JA, Bacon JR, Fortun P, Atherton C, Taylor MA, Hawkey CJ, Barrett DA, Mithen RF. Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli. Am J Clin Nutr 2005; 82:1283–91.
<https://doi.org/10.1093/ajcn/82.6.1283>
7. E, Rimm EB, Liu Y, Stampfer MJ, Willett WC. A prospective study of cruciferous vegetables and prostate cancer. Cancer Epidemiol Biomarkers Prev 2003; 12:1403–09.
8. CA, Riboli E. Diet and cancer prevention: Where we are, where we are going. Nutr Cancer 2006; 56:225–31.
<https://doi.org/10.1207/s15327914nc5602_14>
9. J, Sedlák J, Mithen R, Bao Y. Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochem Pharmacol 2005; 69:1543–52.
<https://doi.org/10.1016/j.bcp.2005.03.015>
10. W-S, Kim I-W, Hu R, Kong A-NT. Modulatory Properties of various natural chemopreventive agents on the activation of NF-κB signaling pathway. Pharm Res 2004; 21:661–70.
<https://doi.org/10.1023/B:PHAM.0000022413.43212.cf>
11. S, Weinberg MS, Banik NL, Patel SJ, Ray SK. Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphane. Neuroscience 2006; 141: 1265–80.
<https://doi.org/10.1016/j.neuroscience.2006.04.075>
12. G, Lichtenberg M, Iori R, Barillari J, Bartsch H, Gerhauser C. Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae. Mutat Res 2006; 599:76–87.
<https://doi.org/10.1016/j.mrfmmm.2006.01.007>
13. L, Courtois A, Loewert M, Guillouzo A, Fardel O. Reactive oxygen species- related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane. Biochem Biophys Res Commun 2001; 282:257–63.
<https://doi.org/10.1006/bbrc.2001.4531>
14. A, Sobolewski MD, Davidson NE. Sulforaphane induces cell typespecific apoptosis in human breast cancer cell lines. Mol Cancer Ther 2007; 6:1013–21.
<https://doi.org/10.1158/1535-7163.MCT-06-0494>
15. SV, Herman-Antosiewicz A, Singh AV, Lew KL, Srivastava SK, Kamath R, Brown KD, Zhang L, Baskaran R. Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. J Biol Chem 2004; 279:25813–22.
<https://doi.org/10.1074/jbc.M313538200>
16. M, Gasper AV, Smith JA, Hawkey CJ, Bao Y, Mithen RF. Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J Nutr 2005; 135:1865–72.
<https://doi.org/10.1093/jn/135.8.1865>
17. DTH, Verhagen H, Goldbohm RA, van den Brandt PA, van Poppel G. A review of mechanisms underlying anticarcinogenicity by brassica vegetables. Chem Biol Interact 1997; 103:79–129.
<https://doi.org/10.1016/S0009-2797(96)03745-3>
18. C-T, Yen G-C. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005; 26:2138–48.
<https://doi.org/10.1093/carcin/bgi185>
19. Y, Li J, Tang L. Cancer-preventive isothiocyanates: dichotomous modulators of oxidative stress. Free Radic Biol Med 2005; 38:70–77.
<https://doi.org/10.1016/j.freeradbiomed.2004.09.033>
