Acta Med. 2007, 50: 171-176

https://doi.org/10.14712/18059694.2017.78

In Vitro Antiproliferative Effects of Sulforaphane on Human Colon Cancer Cell Line SW620

Hana Andělová, Emil Rudolf, Miroslav Červinka

Charles University in Prague, Faculty of Medicine in Hradec Králové, Department of Medical Biology and Genetics, Hradec Králové, Czech Republic

Received June 1, 2007
Accepted August 1, 2007

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  • Santana-Gálvez Jesús, Villela-Castrejón Javier, Serna-Saldívar Sergio O., Cisneros-Zevallos Luis, Jacobo-Velázquez Daniel A.: Synergistic Combinations of Curcumin, Sulforaphane, and Dihydrocaffeic Acid against Human Colon Cancer Cells. IJMS 2020, 21, 3108. <https://doi.org/10.3390/ijms21093108>
  • Pereira Lucília, Silva Patrícia, Duarte Marlene, Rodrigues Liliana, Duarte Catarina, Albuquerque Cristina, Serra Ana: Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study. Nutrients 2017, 9, 368. <https://doi.org/10.3390/nu9040368>
  • Yin Teng-Fei, Wang Min, Qing Ying, Lin Ying-Min, Wu Dong: Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms. WJG 2016, 22, 7058. <https://doi.org/10.3748/wjg.v22.i31.7058>
  • Sestili Piero, Fimognari Carmela: Cytotoxic and Antitumor Activity of Sulforaphane: The Role of Reactive Oxygen Species. BioMed Research International 2015, 2015, 1. <https://doi.org/10.1155/2015/402386>
  • Fimognari Carmela, Turrini Eleonora, Ferruzzi Lorenzo, Lenzi Monia, Hrelia Patrizia: Natural isothiocyanates: Genotoxic potential versus chemoprevention. Mutation Research/Reviews in Mutation Research 2012, 750, 107. <https://doi.org/10.1016/j.mrrev.2011.12.001>
  • Boghossian Shahe, Hawash Ahmed: Chemoprevention in colorectal cancer - where we stand and what we have learned from twenty year's experience. The Surgeon 2012, 10, 43. <https://doi.org/10.1016/j.surge.2011.07.003>
  • Rudolf Emil, Červinka Miroslav: Sulforaphane induces cytotoxicity and lysosome- and mitochondria-dependent cell death in colon cancer cells with deleted p53. Toxicology in Vitro 2011, 25, 1302. <https://doi.org/10.1016/j.tiv.2011.04.019>
  • Rajendran Praveen, Ho Emily, Williams David E, Dashwood Roderick H: Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenet 2011, 3. <https://doi.org/10.1186/1868-7083-3-4>
  • Qazi Aamer, Pal Jagannath, Maitah Ma'in, Fulciniti Mariateresa, Pelluru Dheeraj, Nanjappa Puru, Lee Saem, Batchu Ramesh B., Prasad Madhu, Bryant Christopher S., Rajput Samiyah, Gryaznov Sergei, Beer David G., Weaver Donald W., Munshi Nikhil C., Goyal Raj K., Shammas Masood A.: Anticancer Activity of a Broccoli Derivative, Sulforaphane, in Barrett Adenocarcinoma: Potential Use in Chemoprevention and as Adjuvant in Chemotherapy. Translational Oncology 2010, 3, 389. <https://doi.org/10.1593/tlo.10235>
  • Yu Dong, Sekine-Suzuki Emiko, Xue Lian, Fujimori Akira, Kubota Nobuo, Okayasu Ryuichi: Chemopreventive agent sulforaphane enhances radiosensitivity in human tumor cells. Int. J. Cancer 2009, 125, 1205. <https://doi.org/10.1002/ijc.24480>
  • Rudolf E., Andělová H., Červinka M.: Activation of several concurrent proapoptic pathways by sulforaphane in human colon cancer cells SW620. Food and Chemical Toxicology 2009, 47, 2366. <https://doi.org/10.1016/j.fct.2009.06.034>
  • Sekine-Suzuki Emiko, Yu Dong, Kubota Nobuo, Okayasu Ryuichi, Anzai Kazunori: Sulforaphane induces DNA double strand breaks predominantly repaired by homologous recombination pathway in human cancer cells. Biochemical and Biophysical Research Communications 2008, 377, 341. <https://doi.org/10.1016/j.bbrc.2008.09.150>
  • Mi Lixin, Chung Fung-Lung: Binding to Protein by Isothiocyanates: A Potential Mechanism for Apoptosis Induction in Human Nonsmall Lung Cancer Cells. Nutrition and Cancer 2008, 60, 12. <https://doi.org/10.1080/01635580802381287>
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