Acta Med. 2006, 49: 233-235
https://doi.org/10.14712/18059694.2017.138
Reactivation Potency of New Group of Acetylcholinesterase Reactivators and Their Comparison with Currently Available Oximes
References
1. Bas Clin Pharmacol Toxicol 2004; 95: 81–6.
< J, Kuča K, Kassa J. Specification of the structure of oximes able to reactivate tabun inhibited acetylcholinesterase. https://doi.org/10.1111/j.1742-7843.2004.950207.x>
2. Bioorg Med Chem Lett 2005; 15: 3076–80.
< SR, Vobalaboina V, Garlapati A. Quaternary salts of 4,3’ and 4,4’bis-pyridinium monooximes: Synthesis and biological activity. https://doi.org/10.1016/j.bmcl.2005.04.026>
3. Drug Met Rev 1984; 15: 557–9.
< AP. Design and structure-activity relationships of antidotes to organophosphorus anticholinesterase agents. https://doi.org/10.3109/03602538409029973>
4. J Toxicol Clin Toxicol 2002; 40: 803–16.
< J. Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. https://doi.org/10.1081/CLT-120015840>
5. Mol Chem Neuropathol 1998; 33: 175–84.
< J, Bajgar J. Changes of acetylcholinesterase activity in various parts of brain following nontreated and treated soman poisoning in rats. https://doi.org/10.1007/BF02815180>
6. Toxicology 1999; 132: 111–8.
< J, Cabal J. A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods. https://doi.org/10.1016/S0300-483X(98)00146-2>
7. Pharmacol Toxicol 1999; 84: 41–6.
< J, Cabal J. A comparison of the efficacy of acetylcholine reactivators against cyclohexyl methylphosphonofluoridate (GF agent) by in vitro and in vivo methods. https://doi.org/10.1111/j.1600-0773.1999.tb02109.x>
8. Bioorg Med Chem Lett 2005; 15: 2914–17.
< TH, Kuča K, Jun D, Jung YS. Design and synthesis of new bis-pyridinium oximes as cyclosarin-inhibited acetylcholinesterase reactivators. https://doi.org/10.1016/j.bmcl.2005.03.060>
9. Mini Rev Med Chem 2006; 6: 269–77.
< K, Jun D, Musilek K. Structural requirements of acetylcholinesterase reactivators. https://doi.org/10.2174/138955706776073510>
10. Toxicol Mech Meth 2005; 15: 247–52.
< K, Cabal J. Evaluation of newly synthesized reactivators of the brain cholinesterase inhibited by sarin-nerve agent. https://doi.org/10.1080/15376520590968770>
11. J Enzyme Inhib Med Chem 2004; 19: 39–43.
< K, Patočka J. Reactivation of Cyclosarin-inhibited Rat Brain Acetylcholinesterase by Pyridinium–Oximes. https://doi.org/10.1080/1475636031000163850>
12. Chem Biol 2003; 10: 491–502.
< YP, Kollmeyer TM, Hong F, Lee JC, Hammond PI, Haugabouk SP, Brimijoin S. Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators. https://doi.org/10.1016/S1074-5521(03)00126-1>
13. J Enzyme Inhib Med Chem 2005; 20: 233–7.
< J, Kuča K, Kivala M, Kohout M, Cabal J, Liška F. New group of monoquaternary reactivators of the acetylcholinesterase inhibited by nerve agents. https://doi.org/10.1080/14756360400021858>
14. Arch Toxicol 1996; 70: 497–503.
< F, Kirchner T, Bäcker M, Szinicz L. Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds. https://doi.org/10.1007/s002040050304>
15. Bull Korean Chem Soc 2003; 24: 1368–70.
GY, Yoon JH, Seong CM, Park NS, Jung YS. Synthesis of Bis-pyridinium oxime antidotes using bis(methylsulfonoxymethyl) ether for organophosphate nerve agents.