Mucosal Mast Cells in Irritable Bowel Syndrome and Inflammatory Bowel Disease

Tunc, Bilge; Filik, Levent; Altıntas, Engin; Turhan, Nesrin; Ulker, Aysel; Dağlı, Ülkü

doi:10.14712/18059694.2018.46

Acta Medica > Archive > 2005, Vol. 48 > Issue 3-4 > Mucosal Mast Cells in Irritable Bowel…

Acta Med. 2005, 48: 163-164

https://doi.org/10.14712/18059694.2018.46

Mucosal Mast Cells in Irritable Bowel Syndrome and Inflammatory Bowel Disease

Bilge Tunc^a, Levent Filik^b, Engin Altıntas^a, Nesrin Turhan^c, Aysel Ulker^a, Ülkü Dağlı^a

^aTurkiye Yuksek Ihtisas Hospital, Gastroenterology Clinic, Ankara, Turkey
^bBaşkent University, Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey
^cTurkiye Yuksek Ihtisas Hospital, Division of Pathology, Ankara, Turkey

Received June 1, 2005
Accepted August 1, 2005

Even though exciting progresses have been until now, further studies are necessary to clearly understand the significance of MMC. Mast cells are thought to participate in the pathogenesis of inflammatory bowel disease and irritable bowel syndrome. However, their role in the pathogenesis remains unsettled. The specific aims of this study were to (1) examine mucosal mast cell counts in the cecum in patient with IBS, and IBD (2) compare MMC between the disease groups. We showed increased MMC count in IBS.