Acta Med. 2005, 48: 153-155

https://doi.org/10.14712/18059694.2018.44

Transplantation of Bone Marrow Derived Progenitor Cells in Acute Myocardial Infarction. The First Results

Radek Pudila, Jan Vojáčeka, Stanislav Filipb, Pavel Měřičkac, Josef Šťáseka, Hana Strakováb, Doris Vokurkovád, Miroslav Solařa, Jaroslav Mokrýe, Jan Dominikf, Jaroslav Malýg

aCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, 1st Department of Medicine, Hradec Králové, Czech Republic
bCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Department of Oncology and Radiology, Hradec Králové, Czech Republic
cCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Tissue Bank, Hradec Králové, Czech Republic
dCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Department of Clinical Immunology and Allergology, Hradec Králové, Czech Republic
eCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Department of Histology and Embryology, Hradec Králové, Czech Republic
fCharles University Prague, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Department of Cardiosurgery, Hradec Králové, Czech Republic
gCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Medicine, Hradec Králové, Czech Republic

Received February 1, 2005
Accepted May 1, 2005

References

1. Beltrami AP, Barlucchi L, Torela D et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114:763–76. <https://doi.org/10.1016/S0092-8674(03)00687-1>
2. Britten MD, Abolmaali ND, Assmus B et al. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE- AMI). Mechanistic insights from serial contrast enhanced magnetic resonance imaging. Circulation 2003; 108:2212–8. <https://doi.org/10.1161/01.CIR.0000095788.78169.AF>
3. Fuchs S, Baffour R, Zhou Y et al. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental ischemia. J Am Coll Cardiol 2001; 37:1726–32. <https://doi.org/10.1016/S0735-1097(01)01200-1>
4. Kawamoto A, Gwon HC, Iwaguro H et al. Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation 2001; 103:634–7. <https://doi.org/10.1161/01.CIR.103.5.634>
5. Kocher AA, Schuster MD, Szabolcs MJ et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nature Med 2001; 7:430–6. <https://doi.org/10.1038/86498>
6. Oh H, Bradfute SB, Gallardo TD et al. Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 2003; 100:12313–8. <https://doi.org/10.1073/pnas.2132126100> <PubMed>
7. Orlic D, Kajstura J, Chimenti S et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 2001; 98:10344–49. <https://doi.org/10.1073/pnas.181177898> <PubMed>
8. Quesenberry PJ, Abedi M, Aliotta J et al. Stem cell plasticity: an overview. Blood Cells Mol Dis 2004; 32:1–4. <https://doi.org/10.1016/j.bcmd.2003.09.007>
9. Schachinger V, Assmus B, Britten M et al. Transplantion of progenitor cells and regeneration enhancement in acute myocardial infarction. Final one-year results of the TOPCARE-AMI Trial. J Am Coll Cardiol 2004; 44:1690–99. <https://doi.org/10.1016/j.jacc.2004.08.014>
10. Tse HF, Kwong YL, Chan JFK, Lo G, Ho CL, Lau CP. Angiogenesis in ischemic myocardium by intramyocardial autologous bone marrow cell implantation. Lancet 2003; 361:47–9. <https://doi.org/10.1016/S0140-6736(03)12111-3>
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