Acta Med. 2004, 47: 323-326

Influence of D-Glucose on Lipid Solid Support Membrane System as Attempt for Biosensing of Medically Relevant Molecules

Galina Laputková, Michal Legiň, Ján Sabo

P. J. Šafárik University, Faculty of Medicine, Department of Medical Biophysics, Košice, Slovak Republic

The influence of D-glucose on a lipid solid support system with the aid of impedance spectrocopy as a preliminary attempt for the biosensing of medical relevant molecules was studied. In spite of some shortcomings, s-BLM's proved to be an appropriate model for the study of lipid membrane – D-glucose interactions. The shortcomings were the roughness of the metal support, and the lack of homogeneity in the monolayer or multilayer lipid structures.


This work was supported by internal grant 26/2002-2005 from the Faculty of Medicine of P. J. Safarik University, Kosice, Slovak Republic.


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