Cytologic Differential Diagnostic Problems in Ulcerative Cervicitis

Tamiolakis, Demetrio; Kotini, Athanasia; Koutlaki, Nikoleta; Galazios, Georgios; Liberis, Vasilios; Anastasiadis, Panagiotis

doi:10.14712/18059694.2018.65

Acta Medica > Archive > 2004, Vol. 47 > Issue 1 > Cytologic Differential Diagnostic…

Acta Med. 2004, 47: 43-46

https://doi.org/10.14712/18059694.2018.65

Cytologic Differential Diagnostic Problems in Ulcerative Cervicitis

Demetrio Tamiolakis^a, Athanasia Kotini^b, Nikoleta Koutlaki^c, Georgios Galazios^c, Vasilios Liberis^c, Panagiotis Anastasiadis^c

^aChania Hospital, Depatment of Cytology, Chania, Greece
^bDemocritus University of Thrace, Medical School, Laboratory of Medical Physics, Alexandroupolis, Greece
^cDemocritus University of Thrace, Medical School, Department of Obstetrics & Gynaecology, Alexandroupolis, Greece

Received August 1, 2003
Accepted October 1, 2003

Objective: To improve the detection rates in the determination of signs consistent with ulcerative cervicitis against signs of intraepithelial neoplasia, in PAP smears. Study design: We investigated the frequency of establishing a diagnosis of a simple ulcerative cervicitis by histology in a cohort of 58 females with cervical cytology suggestive of intraepithelial neoplasia. Results: There was found a detection rate of 81.58% in the determination of ulcerative cervicitis by cytology and a rate of 100% in the determination of HPV-infection, CIN1, CIN2 and CIN3 respectively. There was no statistically significant difference between cytology and histology in the diagnosis of ultracerative cervicitis (p>0.5, chi-square). Conclusions: There is an overestimation of the cytological signs in the diagnosis of ulcerative cervicitis 18.42 %). There is also an excellent agreement in the diagnosis of HPV-infection and CIN grades (100 %) between cytology and histology, discordant with the literature (2.4 %–71 %).