Acta Med. 2003, 46: 179-182

https://doi.org/10.14712/18059694.2019.30

Prevalence of CD8/CD4 Ratio in the Fetal Thymic Parenchyme in Down’s Syndrome

Demetrio Tamiolakisa, Ioannis Venizelosb, Athanasia Kotinic, Sylva Nikolaidoua, Nikolaos Papadopoulosd

aGeneral Hospital of Alexandroupolis, Department of Cytology, Greece
bIppokration Hospital of Salonica, Department of Pathology, Greece
cDemocritus University of Thrace, Department of Medical Physics, Greece
dDemocritus University of Thrace, Department of Histology – Embryology, Greece

Received March 1, 2003
Accepted June 1, 2003

References

1. Agus D B, Surh C D, Sprent J. Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med 1991; 173:1039–46. <https://doi.org/10.1084/jem.173.5.1039> <PubMed>
2. Aita M, Franze A, Gabrielli F. S-100 immunoreactive interdigitating cells in normal and in Down’s syndrome human thymuses. Cell Biol Int Rep 1991; 15(8): 645–59. <https://doi.org/10.1016/0309-1651(91)90065-Q>
3. Bannister L. Haemolymphoid System In: Gray’s Anatomy 38th Edition, Churchill Livingstone 1995, chapter 9:1420–1.
4. Fonseca EC, Lannes-Vieira J, Villa-Verde DM, Savino W. Thymic extracellular matrix in Down’s syndrome. Braz J Med Biol Res 1989; 22(8):971–4.
5. Ford CE. Traffic of lymphoid cells in the body. In Wolstenholme G, Porter R, editors: The thymus: experimental and clinical studies, Boston: Little, Brown, 1966:131.
6. Goldstein G. Thymus factors in immunity. Ann N Y Acad Sci 1975; 249:177. <https://doi.org/10.1111/j.1749-6632.1975.tb29067.x>
7. Haynes BF, Denning SM, Singer KH, Kurtzberg J. Ontogeny of T-cell precursors. Immunol Today 1989; 10:87. <https://doi.org/10.1016/0167-5699(89)90232-6>
8. Janossy G, Bofill M, Trejdosiewicz LK et al. Cellular differentiation of lymphoid subpopulations and their microenvironments in the human thymus. In Muller- Hermelink HK, editor: The human thymus: histophysiology and pathology, Berlin: Springer Verlag 1986:89.
9. Janossy G, Prentice HG, Grob JP et al. T lymphocyte regeneration after transplantation of R cell depleted allogeneic bone marrow. Clin Exp Immunol 1986; 63: 577–86.
10. Janossy G, Campana D. Ontogeny of the human T cell receptors–single cell studies. Thymus Update 1989; 2:39–58.
11. Larocca LM, Lauriola L, Ranelletti FO et al. Morphological and immunohistochemical study of Down syndrome thymus. Am J Med Genet Suppl 1990; 7:225–30.
12. Medvedev Niu, Popova ED. Thymus morphology in Down’s syndrome. Arkh Patol 1982; 44(6):27–30.
13. Papadogiannakis N, Svend-Aage J, Olding LB. Suppressor cell activity in human cord blood. In: Chaouat G, editor: The immunology of the fetus, Boca Raton, FL, CRC Press, 1990:215.
front cover

ISSN 1211-4286 (Print) ISSN 1805-9694 (Online)

Open access journal

Archive