Intravascular Large B-Cell Lymphoma Presenting As Cutaneous Panniculitis

Dědič, Karel; Belada, David; Žák, Pavel; Nožička, Zdeněk

doi:10.14712/18059694.2019.19

Acta Medica > Archive > 2003, Vol. 46 > Issue 3 > Intravascular Large B-Cell Lymphoma…

Acta Med. 2003, 46: 121-123

https://doi.org/10.14712/18059694.2019.19

Intravascular Large B-Cell Lymphoma Presenting As Cutaneous Panniculitis

Karel Dědič^a, David Belada^b, Pavel Žák^b, Zdeněk Nožička^a

^aCharles University in Prague, Faculty of Medicine in Hradec Králové, The Fingerland Department of Pathology, Hradec Králové, Czech Republic
^bFaculty Hospital in Hradec Králové, Department of Hematology, Hradec Králové, Czech Republic

Received February 1, 2003
Accepted May 1, 2003

In this report the case of intravascular large B-cell lymphoma (angiotropic lymphoma, intravascular angioendotheliomatosis, malignant endotheliomatosis) with panniculitis features is present. The diagnosis was based on finding of typical CD20 positive tumorous cells within capillaries, veins, and small arteries in the biopsy of subcutaneous adipose tissue. An accurate and early diagnosis together with combined chemotherapy resulted in good response and remission of the disease.