Acta Med. 2002, 45: 83-84

https://doi.org/10.14712/18059694.2019.59

Improvement of Skin Symptoms and Mineral Imbalance by Drinking Deep Sea Water in Patients with Atopic Eczema/Dermatitis Syndrome (AEDS)

Hajime Kimataa, Hideyuki Taib, Koji Nakagawab, Yoshindo Yokoyamab, Hiroshi Nakajimab, Yoshinari Ikegamib

aUnitika Central Hospital, Department of Allergy, Uji-City, Kyoto Prefecture, Japan
bAko Kasei Co., Ltd., Ako-City, Hyogo Prefecture, Japan

Received February 1, 2002
Accepted April 1, 2002

Crossref Cited-by Linking

  • Moini Jazani Arezoo, Ayati Mohammad Hossein, Nadiri Ata Allah, Nasimi Doost Azgomi Ramin: Efficacy of hydrotherapy, spa therapy, and balneotherapy for psoriasis and atopic dermatitis: a systematic review. Int J Dermatology 2023, 62, 177. <https://doi.org/10.1111/ijd.16080>
  • Wu Chia-Chun, Cheng Yu-Hsuan, Chen Kuo-Hsin, Chien Chiang-Ting: Deep Sea Water-Dissolved Organic Matter Intake Improves Hyperlipidemia and Inhibits Thrombus Formation and Vascular Inflammation in High-Fat Diet Hamsters. Life 2022, 12, 82. <https://doi.org/10.3390/life12010082>
  • Takeuchi Hiroaki, Yoshikane Yu, Takenaka Hirotsugu, Kimura Asako, Islam Jahirul Md., Matsuda Reimi, Okamoto Aoi, Hashimoto Yusuke, Yano Rie, Yamaguchi Koichi, Sato Shouichi, Ishizuka Satoshi: Health Effects of Drinking Water Produced from Deep Sea Water: A Randomized Double-Blind Controlled Trial. Nutrients 2022, 14, 581. <https://doi.org/10.3390/nu14030581>
  • Bentivegna Kathryn, Waldman Reid A., Grant-Kels Jane M.: Nutrition and Water. Clinics in Dermatology 2021, 39, 757. <https://doi.org/10.1016/j.clindermatol.2021.05.003>
  • Ma Xiaolei, Duan Mengshan, Duan Duomo, Qiu Jinquan, Cao Junrui: A Study on Comprehensive Evaluation of Multiple-depth Sea Water Quality in the South China Sea. IOP Conf. Ser.: Earth Environ. Sci. 2021, 809, 012013. <https://doi.org/10.1088/1755-1315/809/1/012013>
  • Lu Chieh‐Hsiang, Ou Hsiu‐Chung, Day Cecilia‐Hsuan, Chen Hsiu‐I, Pai Pei‐Ying, Lee Cheng‐Yu, Chen Ray‐Jade, Chang Ruey‐Lin, PadmaViswanadha Vijaya, Hsieh Dennis Jine‐Yuan, Huang Chih‐Yang: Deep sea minerals ameliorate diabetic‐induced inflammation via inhibition of TNFα signaling pathways. Environmental Toxicology 2020, 35, 468. <https://doi.org/10.1002/tox.22882>
  • Nam Jain, Kim Kyeong Jin, Park Geonhee, Kim Byeong Goo, Jeong Gwi-Hwa, Jeon Jong-eun, Hurh Byung Serk, Kim Ji Yeon: Anti-Inflammatory Properties of Mineral-Balanced Deep Sea Water in In-Vitro and In-Vivo Models of Inflamed Intestinal Epithelium. Applied Sciences 2020, 10, 5183. <https://doi.org/10.3390/app10155183>
  • Takeuchi Hiroaki, Higuchi Keiro, Yoshikane Yu, Takagi Ryo, Tokuhiro Shinji, Takenaka Koichi, Oboshi Wataru, Kimura Asako, Islam Jahirul Md., Kaneko Ayami, Sato Shouichi, Ishizuka Satoshi: Drinking Refined Deep-Sea Water Improves the Gut Ecosystem with Beneficial Effects on Intestinal Health in Humans: A Randomized Double-Blind Controlled Trial. Nutrients 2020, 12, 2646. <https://doi.org/10.3390/nu12092646>
  • Lu Chieh-Hsiang, Shen Chia-Yao, Hsieh Dennis Jine-Yuan, Lee Cheng-Yu, Chang Ruey-Lin, Ju Da-Tong, Pai Pei-Ying, Viswanadha Vijaya Padma, Ou Hsiu-Chung, Huang Chih-Yang: Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts. Journal of Applied Physiology 2019, 127, 356. <https://doi.org/10.1152/japplphysiol.00184.2019>
  • Crespo A., Riballo M.J., Guerrero P., Ortega S., Serrano A., Llerena J.L., Béjar F.J., Morán R., Masa M., Liviano D.: Reduction of salt in tomato products through the use of seawater. Acta Hortic. 2019, 225. <https://doi.org/10.17660/ActaHortic.2019.1233.31>
  • Akdeniz M., Tomova‐Simitchieva T., Dobos G., Blume‐Peytavi U., Kottner J.: Does dietary fluid intake affect skin hydration in healthy humans? A systematic literature review. Skin Research and Technology 2018, 24, 459. <https://doi.org/10.1111/srt.12454>
  • YAMAMOTO Tatsuki, YAMADA Katsuhisa, SUZUKI Nobutaka, KYO Hoko, TAKAHASHI Masayuki Mac: Deep Sea Water in the Field of Mibyo and Preventive Medicine：A Japanese Perspective. JJCAM 2018, 15, 67. <https://doi.org/10.1625/jcam.15.67>
  • Lee Chun-Lin: The advantages of deep ocean water for the development of functional fermentation food. Appl Microbiol Biotechnol 2015, 99, 2523. <https://doi.org/10.1007/s00253-015-6430-7>
  • Khokhlov A. N., Morgunova G. V., Ryndina T. S., Coll F.: Pilot study of a potential geroprotector, “Quinton Marine Plasma,” in experiments on cultured cells. Moscow Univ. Biol.Sci. Bull. 2015, 70, 7. <https://doi.org/10.3103/S009639251501006X>
  • Kang Sun Moon, Jhoo Jin Woo, Pak Jae In, Kwon Ill Kyoung, Lee Sung Ki, Kim Gur Yoo: Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice. Journal of Dairy Science 2015, 98, 5967. <https://doi.org/10.3168/jds.2015-9492>
  • Ha Byung Geun, Park Jung‐Eun, Shin Eun Ji, Shon Yun Hee: Effects of balanced deep‐sea water on adipocyte hypertrophy and liver steatosis in high‐fat, diet‐induced obese mice. Obesity 2014, 22, 1669. <https://doi.org/10.1002/oby.20740>
  • Wang Li-Chun, Kuo Iau-Uen, Tsai Tsung-Yu, Lee Chun-Lin: Antrodia camphorata-fermented product cultured in deep ocean water has more liver protection against thioacetamide-induced fibrosis. Appl Microbiol Biotechnol 2013, 97, 9955. <https://doi.org/10.1007/s00253-013-5214-1>
  • Wang Li-Chun, Lung Tzu-Ying, Kung Yi-Hsin, Wang Jyh-Jye, Tsai Tsung-Yu, Wei Bai-Luh, Pan Tzu-Ming, Lee Chun-Lin: Enhanced Anti-Obesity Activities of Red Mold Dioscorea When Fermented Using Deep Ocean Water as the Culture Water. Marine Drugs 2013, 11, 3902. <https://doi.org/10.3390/md11103902>
  • Lee Chun-Lin, Kung Yi-Hsin, Wang Jyh-Jye, Lung Tzu-Ying, Pan Tzu-Ming: Enhanced Hypolipidemic Effect and Safety of Red Mold Dioscorea Cultured in Deep Ocean Water. J. Agric. Food Chem. 2011, 59, 8199. <https://doi.org/10.1021/jf201948v>
  • Hwang Hee Sun, Kim Seon Hwa, Yoo Yung Geun, Chu Yong Shik, Shon Yun Hee, Nam Kyung Soo, Yun Jong Won: Inhibitory Effect of Deep-sea Water on Differentiation of 3T3-L1 Adipocytes. Mar Biotechnol 2009, 11, 161. <https://doi.org/10.1007/s10126-008-9131-8>
  • Hwang Hee Sun, Kim Hyun Ah, Lee Sung Hak, Yun Jong Won: Anti-obesity and Antidiabetic Effects of Deep Sea Water on ob/ob Mice. Mar Biotechnol 2009, 11, 531. <https://doi.org/10.1007/s10126-008-9171-0>
  • Williams S., Krueger N., Davids M., Kraus D., Kerscher M.: Effect of fluid intake on skin physiology: distinct differences between drinking mineral water and tap water. Intern J of Cosmetic Sci 2007, 29, 131. <https://doi.org/10.1111/j.1467-2494.2007.00366.x>
  • Pigatto P.: Efficacité de l’eau thermale d’Avène dans la dermatite atopique légère à modérée. Annales de Dermatologie et de Vénéréologie 2005, 132, 16. <https://doi.org/10.1016/S0151-9638(05)79453-9>
  • Hataguchi Y, Tai H, Nakajima H, Kimata H: Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome. Eur J Clin Nutr 2005, 59, 1093. <https://doi.org/10.1038/sj.ejcn.1602218>
  • Tsuchiya Yasuo, Shimizu Tomihiro, Tazawa Teruyuki, Nakamura Kazutoshi, Yamamoto Masaharu: Effects of hot deep seawater bathing on the immune cell distribution in peripheral blood from healthy young men. Environ Health Prev Med 2003, 8, 161. <https://doi.org/10.1007/BF02897909>
Crossref Cited-by Linking logo