Acta Med. 1999, 42: 9-11

https://doi.org/10.14712/18059694.2019.138

A Comparison of the Efficacy of New Monopyridinium Oximes with the Oxime HI-6 Against Mevinphos in Mice

Jiří Kassa, Jiří Bielavský

Purkyně Military Medical Academy, Department of Toxicology, Hradec Králové, Czech Republic

Received November 1, 1998
Accepted April 1, 1999

References

1. Bardin PGS, van Eeden SF, Moolman JA, Foden AP, Joubert JR. Organophosphate and carbamate poisoning. Arch Intern Med 1994; 154:1433-41. <https://doi.org/10.1001/archinte.1994.00420130020005>
2. Chen H-Ch, Bai D-Y, Jiang Y-P. Effects of HI-6 on muscle acetylcholine receptor: analysis on minimal reaction model. Acta Pharmacol Sin 1996; 17:428-31.
3. Dawson RM. Review of oximes available for treatment of nerve agent poisoning. J Appl Toxicol 1994; 14:317-31. <https://doi.org/10.1002/jat.2550140502>
4. Fest C, Schmidt KJ. The Chemistry of organophosphorus pesticides. 2nd ed. Springer-Verlag, Berlin 1982; p. 360.
5. Grue CE, Fleming WJ, Busby DG, Hill EF. Assessing hazards of organophosphate pesticides to wildlife. Trans North Am Wildl Nat Resour Conf 1983; 48: 200-20.
6. Jokanovic M, Maksimovic M. A comparison of trimedoxime, obidoxime, pralidoxime and HI-6 in the treatment of oral organophosphorus insecticide poisoning in the rat. Arch Toxicol 1995; 70:119-23. <https://doi.org/10.1007/BF02733672>
7. Kassa J. Comparison of efficacy of two oximes (HI-6 and obidoxime) in soman poisoning in rats. Toxicology 1995; 101:167-74. <https://doi.org/10.1016/0300-483X(95)03091-S>
8. Kassa J. The possibilities of treatment of poisoning with organophosphorus insecticides in rats. Voj zdrav Listy 1995; 64:143-6.
9. Kassa J, Bielavský J. The efficacy of monopyridinium (2-PAAM, 2-PAEM) and bispyridinium (obidoxime, HI-6) oximes against mevinphos in mice. Pharmacol Toxicol 1997; 81:144-6. <https://doi.org/10.1111/j.1600-0773.1997.tb00044.x>
10. Koplovitz I, Stewart JR. A comparison of the efficacy of HI-6 and 2-PAM against soman, tabun, sarin and VX in the rabbit. Toxicol Lett 1994; 70:269-79. <https://doi.org/10.1016/0378-4274(94)90121-X>
11. Kostenis E, Cid HMB, Holzgrabe U, Mohr K. Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors. Eur J Pharmacol 1996; 314:385-92. <https://doi.org/10.1016/S0014-2999(96)00568-7>
12. Levine R. Recognized and possible effects of pesticides in humans. In: Handbook of Pesticide Toxicology. General Principle. Academic Press: San Diego 1991; 1:275-360.
13. Marrs TC. Organophosphate poisoning. Pharmacol Ther 1993; 58:51-66. <https://doi.org/10.1016/0163-7258(93)90066-M>
14. Shih T-M. Comparison of several oximes on reactivation of soman-inhibited blood, brain and tissue cholinesterase activity in rats. Arch Toxicol 1993; 67:637-46. <https://doi.org/10.1007/BF01974071>
15. Tallarida R, Murray R. Manual of pharmacological calculation with computer programs. Springer-Verlag: New York 1987;p. 145.
16. Tattersall JEH. Ion channel blockade by oximes and recovery of diaphragm muscle from soman poisoning in vitro. Br J Pharmacol 1993; 108:1006-15. <https://doi.org/10.1111/j.1476-5381.1993.tb13498.x> <PubMed>
17. Teyaratman J. Acute pesticide poisoning: a major global health problem. World Health Stat Q 1990; 43:139-44.
18. Vachek J, Kassa J, Fusek J, Bajgar J. New possibilities of treatment of poisoning with organophosphorus compounds. Sbor věd Prací VLA JEP 1993; 116:67-95.
19. van Helden HPM, Busker RW, Melchers BPC, Bruijnzeel PLB. Pharmacological effects of oximes: how relevant are they? Arch Toxicol 1996; 70:779-86. <https://doi.org/10.1007/s002040050340>
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