Acta Med. 1999, 42: 3-8

The Most Important Microtubule Natural Inhibitors

Jiří Patočkaa, Anna Struneckáb

aPurkyně Military Medical Academy, Department of Toxicology, Hradec Králové, Czech Republic
bCharles University in Prague, Department of Physiology and Developmental Biology, Prague, Czech Republic

Received January 1, 1999
Accepted April 1, 1999

Natural microtubule inhibitors represent chemically very variegated family of structures with strong effect on cytoskeletal functions and the use of them is one of the most frequent therapeutic strategies for carcinoma treatment. The survey of the most important natural microtubule inhibitors is summarized in this paper.


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